[26] Uriarte I, Latasa MU, Carotti S, Fernandez-Barrena MG, Garcia-Irigoyen O, Elizalde M, et al. Ileal FGF15 contributes to fifibrosis-associated hepatocellular carcinoma development. Int J Canc 2015;136:2469–2475. [27...
⌈ByDrug医药新闻摘要⌋ 2023-08-17 08:00,普利制药300630:普利制药通过 合成生物学 技术成功开发熊去氧胆酸(英文名:Ursodeoxycholic Acid,UDCA)。 该产品通过基因工程菌株采用多酶联合催化特定底物的方法获得,产品纯度达到99%以上。 熊去氧胆酸(UDCA)。...
We then use the over-the-counter compound z-guggulsterone (ZGG) and the off-patent drug ursodeoxycholic acid (UDCA) to reduce FXR signalling and downregulate ACE2 in human lung, cholangiocyte and intestinal organoids and in the corresponding tissues in mice and hamsters. We demonstrate that ...
·237 P a1.Clinicalfeaturesand of 5.CrosignaniA,BattezzatiM,InvernizziPet managementprimary JGastroenterol 13-3327 2008;1 biliarycirrhosis【J】,World 4(21):33 6.Beuers andsitesofactionof acidin U.Druginsight:Mechanisms ursodeoxycholiccholestasis, NatC1in 1 PractGastroenterol 8328 2006;2(6)I:3...
Drug Invest 1992; 4:83-89; IHC发生率发生率 0 20 40 60 80 43 54 肝硬化肝硬化 67 32 53 35 55 原发性原发性 胆汁性胆汁性 肝硬化肝硬化 原发性原发性 硬化性硬化性 胆管炎胆管炎 药物相药物相 关性肝关性肝 炎炎 自身免自身免 疫性肝疫性肝 炎炎 酒精性酒精性 肝炎肝炎 慢性肝炎慢性肝炎 ...
The article discusses the potential use of ursodeoxycholic acid (UDCA), a drug commonly used to treat liver disease, in the prevention and treatment of COVID-19. The authors conducted a study using administrative databases from Lombardy, Italy to investigate the impact of UDCA treatment on SARS-...
产品活性:Ursodiol能降低胆固醇吸收,可作用于胆结石的溶解。 研究领域:Metabolic Enzyme/Protease 作用靶点:Endogenous Metabolite 相关产品:Human Endogenous Metabolite Compound Library | FDA-Approved Drug Library Plus | Drug Repurposing Compound Library | Natural Product Library Plus | FDA-Approved Drug Library ...
Jiangsu Key Laboratory of Drug ScreeningChina Pharmaceutical UniversityNanjingPeople's Republic of ChinaZhenzhou JiangJiangsu Key Laboratory of Drug ScreeningChina Pharmaceutical UniversityNanjingPeople's Republic of ChinaLuyong ZhangJiangsu Key Laboratory of Drug ScreeningChina Pharmaceutical UniversityNanjing...
for the site-specific delivery of the drug (28). It is known that aminopeptidase activity increases from the ligament of Treitz to the distal ileum (28-31). Among the host of brush border peptidases, aminopeptidase A, in particular, is able to ...
The Food and Drug Administration's Gastrointestinal Drugs Advisory Committee has stated that UDCA is safe and effective for the treatment of primary biliary cirrhosis. More recent Meta-analysis have cast doubt on the real impact of UDCA in patients with PBC. However more recent articles and ...