(1989). Binding sites of ubiquitin- protein ligase. Binding of ubiquitin-protein conjugates and of ubiquitin-carrier protein. J. Biol. Chem. 264,10378-10383.Reiss Y,Heller H,Hershko A.Binding Sites of Ubiquitin-Protein Ligase. Binding of Ubiquitin-Protein Conjugates and of Ubiquitin-Carrier ...
Ubiquitin Protein Ligase E3 is a protein that acts as an E3 ligase in the ubiquitin pathway, transferring activated ubiquitin to target proteins for degradation by the 26S proteasome, thereby regulating cellular protein homeostasis. AI generated definition based on:Brain and Development,2005 ...
Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na[sup +] channel. 来自 EBSCO 喜欢 0 阅读量: 25 作者:McDonald,Fiona,J.,Western,Andrea,H.,McNeil,John,D.,Thomas 摘要: Studies the regulation of the epithelial sodium channel (ENaC) by the ubiquitin-protein ligase. ...
DTX1重组蛋白-别名：Dtx1E3 ubiquitin-protein ligase DTX1 引言DTX1（Delta-like protein (Drosophila) containing REEPP (Arg Glu Glu Pro Pro) motifs 1）是一种重要的E3泛素连接酶，参与了细胞周期的调控、信号转导通路的调节以及蛋白质的降解等生物学过程。目前，科学家们已经成功地实现了DTX1的重组，通过基...
Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP Hyper-phosphorylated tau accumulates in Alzheimer’s disease; but the roles of these phosphorylation sites are unclear. Here the authors show that phosphorylation of a single site, pSer416, limits its tur...
Ubiquitin ligases can also be multi-subunit protein complexes, an arrangement that affords additional layers of regulation to optimize the specificity of and fine-tune the regulation of the assembled ligase complex. Each subunit harbors a unique function of either: (i) facilitating the transfer of ...
英文名称:Anti-E3 ubiquitin ligase/RNF218 别名:C1orf166; E3 ubiquitin ligase; E3 ubiquitin protein ligase MUL1; FLJ12875; GIDE; Growth inhibition and death E3 ligase; MAPL; Mitochondrial anchored protein ligase; Mitochondrial ubiquitin ligase activator of NFKB 1; MUL1; MULAN; Putative NF kappa...
E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) (C-Term) 抗体 公司简介 上海钰博生物科技有限公司是2012年5月由“海归”组成的创业团队与两个专业投资机构发起成立的,以开发生产科研试剂和特色检验产品为方向,经过两年多的努力,已经建立了免疫学和分子生物学的五个技术平台,开发了ELISA/ELISpot酶联免疫试剂盒、重组蛋...
We aimed to reveal the role of ring finger protein 5 (RNF5), an ER‐localized E3 ubiquitin‐protein ligase, in NASH and to explore its underlying mechanism. Approach and Results We first inspected the expression level of RNF5 and found that it was markedly decreased in livers with NASH in...
regulation of ubiquitin-protein ligase activity 青云英语翻译 请在下面的文本框内输入文字,然后点击开始翻译按钮进行翻译,如果您看不到结果,请重新翻译! 翻译结果1翻译结果2翻译结果3翻译结果4翻译结果5 翻译结果1复制译文编辑译文朗读译文返回顶部 泛素蛋白连接酶的活性的调控...