1.As key members of the protein degradation enzymatic system, the function of E3 ubiquitin ligases has been extensively investigated.作为该系统中行使调控降解功能的核心成员,E3泛素连接酶的重要作用已经越来越引起人们的重视。 英文短句/例句 1.Overexpression of E3 Ubiquitin Ligase CHIP Induces Mitotic Catastr...
Binding sites of ubiquitin-protein ligase. J. Biol. Chem. 264:10378-10383.Reiss Y, Heller H, Hershko A 1989 Binding sites of ubiquitin-protein ligase. Binding of ubiquitin-protein conjugates and of ubiquitin-carrier protein. J Biol Chem 264:10378 -10383...
(Figure 2). In recent years, several newubiquitin ligaserecognition motifs have been reported. For example, an F-box-containing protein, Fbx2, with no known binding specificity was recently reported to recognize N-linked high-mannoseoligosaccharidesbound to proteins[1]. Recognition ofN-gly...
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2) E3 ubiquitin protein ligase 泛素蛋白连接酶 1. Now it is believed that Parkin functions as an E3 ubiquitin protein ligase which involves in protein s ubiquitination. 现认为Parkin行使泛素蛋白连接酶功能,参与蛋白质的泛素化过程。 更多例句>> 3) Ubiquitin-protein ligases(E3) 泛素-蛋白连接酶 ...
Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP Hyper-phosphorylated tau accumulates in Alzheimer’s disease; but the roles of these phosphorylation sites are unclear. Here the authors show that phosphorylation of a single site, pSer416, limits its tur...
While there are few E1-activating enzymes (5 genes) and a little more E2-conjugating enzymes (37 genes), there are hundreds of E3-ubiquitin protein ligases. The search string “E3-ubiquitin protein ligase” produces 383 reviewed entries in UniProt forHomo sapiens. Five classes of E3s are reco...
Ubiquitin-protein ligases 喜欢 0 阅读量: 43 作者: Robinson,A P. 展开 摘要: J Cell Sci. 2004 Oct 15;117(Pt 22):5191-4. Review 展开 关键词: Animals Humans Ubiquitin-Protein Ligases Models, Biological Ubiquitin DOI: 10.1242/jcs.01539 被引量: 167 年份: 2004 ...
网络泛素连接酶;泛素链接酶;蛋白连接酶 网络释义
产品名称:人E3泛素蛋白连接酶AMFR (E3 ubiquitin-protein ligase AMFR)CLIA试剂盒 英文名称:CLIA Kit for Human E3 ubiquitin-protein ligase AMFR 基因/抗原:AMFR 别名:E3 ubiquitin-protein ligase AMFR, Autocrine motility factor receptor, isoform 2, AMF receptor, isoform 2, RING finger protein 45, gp78,...