Ubiquitin Protein Ligase E3 is a protein that acts as an E3 ligase in the ubiquitin pathway, transferring activated ubiquitin to target proteins for degradation by the 26S proteasome, thereby regulating cellular protein homeostasis. AI generated definition based on:Brain and Development,2005 ...
Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP Hyper-phosphorylated tau accumulates in Alzheimer’s disease; but the roles of these phosphorylation sites are unclear. Here the authors show that phosphorylation of a single site, pSer416, limits its tur...
[cullins, S-phase kinase associated protein-1 (SKP1), Elongin-C (EloC), damage-specific DNA binding protein 1 (DDB1), BTB, or Apc2 proteins.[47,48]. In this review we focus on multi-subunit ligase complexes that are assembled on a cullin–RBX scaffold [cullin/RING ligases (CRLs)]...
E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) (C-Term) 抗体 公司简介 上海钰博生物科技有限公司是2012年5月由“海归”组成的创业团队与两个专业投资机构发起成立的,以开发生产科研试剂和特色检验产品为方向,经过两年多的努力,已经建立了免疫学和分子生物学的五个技术平台,开发了ELISA/ELISpot酶联免疫试剂盒、重组蛋...
人E3泛素蛋白连接酶AMFR (E3 ubiquitin-protein ligase AMFR)CLIA试剂盒 价格电议 起批量≥1 盒 最小起订1盒 供货总量46盒 发货地址上海市闵行区 建议售价￥电询/盒 更新日期2025年01月17日 产品规格96T 即时洽谈立即询价查看联系方式 收藏产品发送留言 ...
2022). Another report demonstrated that an artificial chimera protein with Rspo furin domain for ligase binding and extracellular domain of PD-1 can degrade the target protein PD-L1 and induce T cell activation to suppress tumor growth (ROTACs) (Sun et al. 2023). Therefore, further development...
Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1 来自 国家科技图书文献中心 喜欢 0 阅读量: 51 作者: SHIGETSUGU HATAKEYAMA,MICHIKO SHIRANE 摘要: Activation of the transcription factor nuclear factor kappa B (NF-kb...
in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. ...
Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively...
网络泛素连接酶;泛素链接酶;蛋白连接酶 网络释义