在一项新的验证研究中,Westermark团队发现从美国标准生物品收藏中心(ATCC)购买到的U87MG细胞系与乌普萨拉大学最初建立的U87MG细胞系不是一样的。相关研究结果发表在2016年8月31日那期Science Translational Medicine期刊上,论文标题为“Origin of the U87MG glioma cell line: Good news and bad news”。 《科学家》...
However, based on current literature, the cell line is still of glioblastoma origin and the discrepancy of gender is not unusual. It is possible that the cell line was misidentified in the depositor's original publication. U87MG细胞技术参数 种属来源: 人 组织来源: 脑 疾病类型: 胶质母细胞瘤;...
相关研究结果发表在2016年8月31日那期Science Translational Medicine期刊上,论文标题为“Origin of the U87MG glioma cell line: Good news and bad news”。 《科学家》杂志与Westermark谈论起他的团队对U87MG细胞系的最新分析结果。 《科学家》:是什么让你质疑这种细胞系的纯度? Westermark:在我的论文中我研究...
在一项新的验证研究中,Westermark团队发现从美国标准生物品收藏中心(ATCC)购买到的U87MG细胞系与乌普萨拉大学最初建立的U87MG细胞系不是一样的。相关研究结果发表在2016年8月31日那期Science Translational Medicine期刊上,论文标题为“Origin of the U87MG glioma cell line: Good news and bad news”。 《科学家》...
As described in PubMed=27582061 it is most probably also a glioblastoma cell line but whose origin is unknow. See U-87MG Uppsala (Cellosaurus=CVCL_GP63) for the original U-87MG cell line.该细胞通过慢病毒转染的方式携带Luc基因。 细胞名称 U87MG+luc 人脑星形胶质母细胞瘤稳定表达荧光素酶 ...
Biserova K et al (2021) Cancer stem cells: significance in origin, pathogenesis and treatment of glioblastoma. Cells 10:621. https://doi.org/10.3390/cells10030621 Article CAS PubMed PubMed Central Google Scholar Louis DN et al (2021) The 2021 WHO classification of tumors of the central ner...
These studies have helped define the action of TMZ in cancer cells of mostly hemopoietic origin. However, the action of TMZ in glioblastoma cells remains largely undefined. Glioblastomas are relatively resistant to anti-cancer agents that cause apoptosis via DNA alkylation. Therefore, we have ...
enhanced by ATRA, of interest for chemotherapy targeting studies. ATRA triggered diverse expression patterns of long non-coding RNAsPARTICLEandGAS5in the leading edge and established monolayer growth zone microenvironment. Karyotyping confirmed the female origin of U87MG sourced from Europe. Passaging ...
therapeutic alternative in the hypoxic condition that characterizes GBM, as a result, the cell-cycle is arrested, and cell growth is inhibited in U87MG and U373MG cells. Although there are concerns about the provenance of the U87MG cell line, it is still assumed to be a glioma cell line ...
Glioblastoma, or grade IV astrocytoma, as classified by the World Health Organization (WHO), is a tumor of glial origin restricted to the central nervous system (CNS) that is highly invasive to the surrounding cerebral parenchyma [16,17]. Despite advances in knowledge regarding the molecular ...