serial in vitro passage, suggested that passage-induced changes may lead to notable changes of biological characteristics and several molecular transitions in cancer cell lines, indicating the necessity to shorten experiment-span and accomplish experiments with the same or similar passage cancer cell ...
5) glioma cell U87胶质瘤 1. Knockdown of OPN by OPN-RNAi inhibits growth and invasiveness of U87 glioma cells OPN基因RNAi对U87胶质瘤细胞生长和侵袭的抑制作用 更多例句>> 6) U87 cells U87细胞 1. Effects of VEGFR-2 siRNA on biological characteristics of VEGFR-2 receptor-positive U87 cells...
of clinical treatments to overcome drug resistance. CIK as a novel therapeutic have been employed in the clinical treatment of tumors due to their high tumoricidal activity, low side effects and other characteristics. Given the promising application prospect of this method, it is necessary to ...
Thymoquinone is one of the drugs that exhibits inhibitory characteristics based on in vivo and in vitro models. Aim: This study further investigates the effects of thymoquinone on human global gene expression from opioid receptor expressing cell line (OREC) using RNA sequencing technology. The cell...
MATERIALS AND METHODS: U87MG cells (Human glioblastoma cell line) were treated with Rg3, measured cell viability using MTT assay and trypan blue exclusion assay. The apoptotic characteristics were detected by TUNEL assay, flow cytometry analysis and western blotting. The molecular mechanisms wer...
4)Cell line U87细胞系U87 5)glioma cellU87胶质瘤 1.Knockdown of OPN by OPN-RNAi inhibits growth and invasiveness of U87 glioma cellsOPN基因RNAi对U87胶质瘤细胞生长和侵袭的抑制作用 6)U87 cellsU87细胞 1.Effects of VEGFR-2 siRNA on biological characteristics of VEGFR-2 receptor-positive U87 cells...
This study aimed to investigate the proliferative characteristics, gene expression profile and karyotype of U87MG (ECACC 89081402) post ATRA exposure to highlight subtle challenges associated with this widely utilized laboratory cell line. Given the discrepancy that evidently occurred previously between ...
Table 1.The primer sequences and amplified characteristics. Transcripts of VEGF-A, Quek1 (quail receptor for VEGF-A), interleukin 8, TLR-7, interferon α, and GAPDH (glyceraldehyde-3-phosphate dehydrogenase) were analyzed using LightCycler®Nano (Roche). Final data were normalized to GAPDH mRN...
There are two possible explanations for this: First, it can be postulated from the characteristics of SPARC, which is a secreted form of protein from tumor cells. SPARC is known to facilitate albumin accumulation in tumor stroma [12,38]. As the in vitro environment is somewhat different to ...