PD-L1 expression on the surface of immune cells and tumor cells generates immune resist- ance upon binding to programmed cell death protein 1 (PD-1). On the other hand, intracellular PD-L1 promotes cell growth, proliferation, and migration. Highly aggressive GBM tumors express higher levels of...
800 × g; duration, 20 min) with lymphocyte separation medium (density, 1.077±0.002). The mononuclear cells were re-suspended in cell culture medium (Beyotime Institute of Biotechnology, Shanghai, China) to a density of 4.0×106/ml. On day 0, the cells...
Interestingly, this peptide contains a sequence WR, predicting the same structural characteristics of the W2K3 sequence in the AaTs-1 peptide. Therefore, these two dipeptides were aligned together in the guiding local alignment. The conformations of I1 and S4 of AaTs-1 were only modeled using ...
Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity. Dis. Model. Mech. 2016, 9, 199–210. [CrossRef] [PubMed] 12. Geiger, G.A.; Fu, W.; Kao, G.D. Temozolomide-mediated radiosensitization of human glioma cells in a ...