antigen tolerance, and immune evasion. In HCC, CCL22, which can induce CCR4+Treg cells migration into the TME, was upregulated under sorafenib administration. Its upregulation was mediated by TNFα-related receptor-interacting serine/threonine-protein kinase 1 (RIPK1)/NF-κB pathway,223and TGF-...
英文名称Protein Tyrosine Kinase Inhibitors 储存温度避光,-20°C储存,充氩 运输条件超低温冰袋运输 作用类型抑制剂 作用机制血管内皮生长因子受体 2 抑制剂 产品介绍 Apatinib(YN-968D1) is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM. ...
protein kinase inhibitorsignal transduction inhibitorsynthesis ofSummary Gleevec; (imatinib mesylate) is a protein kinase inhibitor, the first marketed drug whose mechanism of action (MOA) is through inhibition of a protein kinase, functioning as a signal transduction inhibitor (STI). In 2002, it ...
tyrosine kinase inhibitor Thesaurus Medical Acronyms Wikipedia n. Any of a class of drugs, such as imatinib, that target and block the action of specific tyrosine kinases and are used especially in the treatment of chronic myelogenous leukemia and other cancers. ...
Protein tyrosine kinase inhibitor PTK is a group of enzymes, which catalyze the phosphate group in the ATP to be transferred to the many important tyrosine residues in the protein, resulting in residues phosphorylation, thereby activating various substrates enzymes, affecting the growth, proliferation ...
英文名称:Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) 用途:科研 纯度:98% CAS编号:247171-44-4 产地:中国 品牌:Chemstan 包装规格:1mg 货号:CS10664 是否进口:否 Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide corresponding to amino acids 475 to 491 of mouse JAK2, a membe...
2) tyrosine kinase inhibitor 酪氨酸蛋白激酶抑制剂 1. Objective To assess the effect of tyrosine kinase inhibitor (2,5-MC) on the inhibition of in-stent inti-mal hyperplasia. 目的评估酪氨酸蛋白激酶抑制剂2,5-MC抑制支架植入术后内膜增殖的效果。 更多例句>> 3) protein tyrosine kinase inhibitor...
Next, to confirm that IVIG induced Fc[gamma]R activation, we added two novelprotein tyrosine kinase inhibitors, the Hck/Lyn inhibitor PP2 and Syk inhibitor piceatannol, to the culture of LPS-stimulated BMDC together with IVIG and evaluated both IL-10 production and the phosphorylation of ERK1/...
The effect of protein tyrosine kinase inhibitor on inflammatory factors induced nitric oxide production in synovial cells 蛋白酪氨酸激酶抑制剂对炎性因子诱导滑膜细胞产生一氧化氮的影响 168.160.184.82:8080 9. Effect of tyrosine kinase inhibitor on proliferation of human keratinocytes cultured in vitro 酪氨...
Tyrosine kinase inhibitor 1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively. ChemeGen 作为优秀的抑制剂、激动剂及新型生命科学试剂的供应商,致力于为广大科研、商业实验室的科学研究者提供高品质的产品与技术服务,不断促进...