This has made the Abl kinase an attractive target for therapeutic intervention. The introduction of imatinib mesylate (formerly STI571; Gleevect or Glivecs) to the therapeutic armamentarium has changed the current management of CML. Imatinib is a small-molecule inhibitor of the Bcr-Abl tyrosine ...
英文名称:Tyrosine kinase inhibitor 产品货号:M02479 产品规格:1mL(10mM)|5mg 本产品为酪氨酸激酶抑制剂。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途! CAS号:1021950-26-4 纯度:99.78% 分子式:C??H??FN?O? 分子量:586.61 结构式:
C. et al. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood 96, 925–932 (2000). CAS PubMed Google Scholar Hunter, T. Treatment for chronic myelogenous leukemia: the long road to imatinib. J. Clin. Invest. 117, 2036–2043 ...
The second promising tyrosine kinase inhibitor against MTC,motesanib diphosphate(AMG-706), is a multikinase inhibitor targeting VEGF, platelet-derived growth factor, and Kit receptors, which lead toantiangiogenicand directantitumor activity. In a phase I trial with AMG-706, one patient with MTC exhi...
Sunitinib is a multitargeted receptor tyrosine kinase inhibitor approved fo... EW Mueller,ML Rockey,MC Rashkin - 《Pharmacotherapy the Journal of Human Pharmacology & Drug Therapy》 被引量: 62发表: 2008年 A case of Pasteurella multocida peritoneal dialysis-associated peritonitis and review of the ...
Tyrosine kinase inhibitor产品规格:1mL(10mM)|5mg发货周期:1～3天产品价格:询价本产品仅可用于科研实验,严禁用于其他非科研用途!本产品为酪氨酸激酶抑制剂。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:1021950-26-4纯度:99.78%分子式:C31H31FN6O5分子量:586.61结构式:储存条件:-20℃,有效期2...
The remarkable success of BCR-ABL tyrosine kinase inhibitor imatinib (STI571) in the treatment of chronic myeloid leukaemia has particularly stimulated intense research in this field. At least 30 inhibitors are in various stages of clinical development in cancer, and about 120 clinical trials are ...
In this preclinical study, we tested three tyrosine-kinase inhibitors (TKIs): SU5402, a selective inhibitor of fibroblast growth factor receptor (FGFR)-1 and vascular endothelial growth factor receptor (VEGFR)-2; sulfatinib, an inhibitor of FGFR-1 and VEGFR-1, -2, -3; and SPP86, a RET...
现货CAS:1021950-26-4 Tyrosine kinase inhibitor 酪氨酸激酶抑制剂 C31H31FN6O5 纯度:98% 药物活性分子; 原料药 现有大量抑制剂,化学试剂,中间体,原料药现货,并提供定制,纯度都在98%以上,随货提供相应图谱。仅供实验用,质检严格,售后保障。 公司简介 上海瀚香于08年在上海成立,后在武汉设立分部。前体为上海...
Patient Flow Diagram View LargeDownload MMR indicates major molecular response; PRO, patient-reported outcome; and TKI, tyrosine kinase inhibitor. Figure 2. Probability of Molecular Relapse-Free Survival, Treatment-Free Remission (TFR), and Molecular Recurrence (MRec) View LargeDownload A, Kaplan-...