Using Different Types Of Genomic DNA Libraries Enables Sequencing And Scaffolding Of Genomes Of Any SizeDr. Georg Gradl
et al. Hypomethylation of intragenic LINE-1 represses transcription in cancer cells through AGO2. PLoS One 6, e17934 (2011). Article CAS Google Scholar Aporntewan, C. & Mutirangura, A. Connection up- and down-regulation expression analysis of microarrays (CU-DREAM): a physiogenomic ...
Such characterization contributes valuable insight to EWS/FLI transcription factor biology and clarifies the role of GGAA-microsatellites on a global genomic scale. This may provide unique perspective on the role of non-coding DNA in cancer susceptibility and therapeutic development. 展开 ...
The advantages and disadvantages of giving a valid name to a sequence of DNA detected from environmental specimens is presently a hot debate amongst the my
supported in part through the computational resources and staff expertise provided by the Department of Scientific Computing at the Icahn School of Medicine at Mount Sinai. Author information Authors and Affiliations Department of Genetics and Genomic Sciences and Icahn Institute for Genomics and Multi...
By integrating a multitude of genomic data, we found that VMRs enrich for histone modifications indicative of enhancers, suggesting their role as regulatory elements marking cell type specificity. VMRs enriched for transcription factor binding sites in a tissue-dependent manner. Importantly, they ...
We have searched for mutations of the CHM gene in patients with choroideremia by analysis of individual CHM exons and adjacent intronic sequences PCR-amplified from genomic DNA and by reverse transcription (RT)-PCR analysis of the coding region of the CHM mRNA. In 35 patients, at least 21 ...
Detection and molecular monitoring of FIP1L1-PDGFRA-positive disease by analysis of patient-specific genomic DNA fusion junctions To evaluate current detection methods for -in (HES), we developed a means to rapidly amplify genomic break points. We screened 202 cases and detected genom... J Score...
The following genomic relationships among cancer types are shown based on the following subsets of patients: (A) all patients (ALL); (B) basal-like breast cancer (BASAL-LIKE); (C) ovarian cancer (OVARIAN); (D) squamous cell lung cancer (SQCLC); (E) lung adenocarcinoma (LUAD); (F) ...
Variant genotyping. Genomic DNA was extracted from leucocytes of venous blood using the phenol-chloroform method. Genotyping was performed in each population separately with PCR and Sanger sequencing. The PCR products of the samples were sequenced with a sequencer ABI Prism 3100 Genetic Analyzer (...