Focuses on a study which reported the discovery of another abundant species of DNA (cytosine-5) methyltransferase in various types of human cell lines and somatic tissues. Methodology of the study; Results and discussion; Conclusion.HsuDuen-Wei...
Errors during DNA replication are not the only reason why mutations arise in DNA.Mutations, variations in the nucleotide sequence of a genome, can also occur because of damage to DNA. Such mutations may be of two types: induced or spontaneous.Induced mutationsare those that result from an expo...
1992. Two major types of JC virus defined in progressive multifocal leukoencephalopathy brain by early and late coding region DNA sequences. J. Gen. Virol... H Ikegaya,H Iwase,HY Zheng,... - 《Journal of Virological Methods》 被引量: 8发表: 2005年 Pathogenesis and molecular biology of ...
The relative contributions of sexual and asexual reproduction to the genetic structure of populations can be difficult to determine for fungi that use a mixture of both types of propagation. Nuclear RFLPs and DNA fingerprints were used to make indirect and direct measures of departures from random...
Kok K, Osinga J, Carritt B, Davis MB, van der Hout AH, van der Veen AY, Landsvater RM, de Leij LFMH, Berendsen HH, Postmus PE, Poppema S, Buys CHCM (1987): Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer. Nature (London) 330:...
The key step in BWB was to use parentage analysis to reconstruct the family, that is, to use genetic markers to trace the male parent of half-sibling families. The markers used for paternity analysis mainly include random amplification polymorphic DNA (RAPD)8, amplified fragment length ...
The development of methodologies to identify the molecular lesions responsible for different types of -thalassemia has made it possible to correlate these data with clinical and hematological severity. We examined DNA from 35 patients with -thalassemia, residents of the State of So Paulo, Brazil, for...
Background: RNases H are present in all organisms and cleave RNAs in RNA/DNA hybrids. There are two major types of RNases H that have little similarity in sequence, size and specificity. The structure of RNase HI, the smaller enzyme and most abundant in bacteria, has been extensively stu...
The cause of diversity of rat globins was discussed in terms of the nucleotide sequences of cDNAs and known amino acid sequences of globins. 展开 关键词: Animals Rats, Inbred Strains Rats Reticulocytes DNA Globins Cloning, Molecular Base Sequence Amino Acid Sequence Male ...
1a). Following three days, to allow for viral integration and elimination of the majority of non-integrating virus, cells were harvested, DNA and RNA was generated, and barcodes sequenced. MPRA was conducted with three independent replicates and analyzed using MPRAflow23 which found all replicates...