By exploiting recent advances in modern artificial intelligence and large-scale functional genomic datasets, sequence-to-function models learn the relationship between genomic DNA and its multilayer gene regulatory functions. These models are poised to uncover mechanistic relationships across layers of cellula...
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diversity in the genus, its organization and distribution, and its evolutionary history. Of special importance is the formation of a single polyploid from two (among 8) diploid genome types, the radiation of this polyploid, and the domestication and improvement of two (among 5 extant) polyploid ...
These in vivo and in vitro studies highlight the critical role of IGF2 in ovarian follicular development [24] and its relevance to poultry egg-laying traits. FGFR4, a protein-coding gene, plays a regulatory role in various pathways, including cell proliferation, differentiation, migration, and ...
(APP) through its sequential cleavage by two enzymes: β-secretase and γ-secretase [3]. This finding was later confirmed by genetic mutations inAPPin 1991 [7] and presenilins (PSEN1andPSEN2) in 1995 [8,9]. The above genomic studies support an evident molecular mechanism underlying AD, ...
next two nodes up in the tree. This suggests that hyphae evolved either in one of the BCZ nodes or that its evolution was a gradual process unfolding in these three nodes. This distribution also reflects the diverse hypha-like morphologies in the Blastocladio- and Chytridiomycota and is ...
Huawei says that a storage system should deliver at least 6 GB/s of data to ensure its accuracy, completeness, and consistency. Huawei's HPDA Solution offers 32 GB/s bandwidth, more than five times the minimal level designated. And while it used to take 13 years to fully sequence the gen...
These common SNPs were manually inspected using SAMtools (version 0.1.7) [15] and its in-built function, Tview, for visualising the mapping of reads at each SNP position. SNPs identified from BWA mapping were further filtered using SAMtools by SNP quality. Any SNPs with quality score of ...
NRPminer classifies a PSM as statistically significant if its p value is below the default conservative threshold 10−15. The number of distinct NRPs and NRP families was estimated using MS-Cluster60 and SpecNets50 using the threshold cos < 0.7 (see “Methods” section). Two peptides ...
(2010). Breeding and application of late japonica CMS line Yongjing 2A and its late indica-japonica hybrid rice combinations. Hybrid Rice 25, 185–189. CAS Google Scholar Ma, W., Li, J., Qu, B., He, X., Zhao, X., Li, B., Fu, X., and Tong, Y. (2014). Auxin biosynthetic...