Each type of cells is specialised to carry out a particular function, either solely, but usually by forming a particular tissue. Different tissues then combine and form specific organs, where the organ is like a factory where every type of cell has its own job. Since every tissue has its...
There is growing evidence on consequences of direct damage to a cell, as well as on responses of adjacent and infiltrating cells, which also have an effect on the pathology. In this study, by focusing on different pathways of cell death in different vascular diseases, an attempt is made to...
Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type to the dysfun
Despite the fast growing knowledge about the components of the signalling pathways involved in the activation of drought-, cold-, osmotic stress- and salt-responsive genes, relatively little is known about the sensor types responsible for the induction of the pathways. It is thought that different...
C. et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell 10, 520–530 (2012). Article CAS PubMed PubMed Central Google Scholar Florian, M. C. et al. A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing. Nature 503...
Cell–cell signalling in sexual chemotaxis: a basis for gametic differentiation, mating types and sexes. J. R. Soc. Interface 12, 20150342 (2015). PubMed PubMed Central Google Scholar James, T. Y. Why mushrooms have evolved to be so promiscuous: insights from evolutionary and ecological ...
Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type to the dysfun
Here, we unveiled the feature genes in different cell types of the human and mouse gut through single-cell RNA sequencing analysis. Further, the locations of some specific transcription factors and membrane proteins were determined by immunofluorescence staining, and their role in regulating the ...
IPA revealed an important upregulation of (1) various signalling mediators, including eicosanoids, TREM1, and IL17; (2) several signalling pathways involved in the regulation of inflammation, immune response, and tumour progression including, oxytocin, ID1, activin inhibition, MSP-RON, IL33, and...
ARTICLE Received 21 Jan 2015 | Accepted 10 Jul 2015 | Published 18 Aug 2015 | Updated 29 Oct 2015 DOI: 10.1038/ncomms9040 BMP signalling differentially regulates distinct haematopoietic stem cell types OPEN Mihaela Crisan1,2, Parham Solaimani Kartalaei1,2, Chris S. Vink1,2, Tomoko Yamada-...