Acylation of the N-terminal Cys residue is an essential, ubiquitous, and uniquely bacterial posttranslational modification that allows anchoring of proteins to the lipid membrane. In Gram-negative bacteria, acylation proceeds through thr... Serebryakova,Marina,V.,... - 《Journal of Biological Chem...
Scriptaid/exercise-induced lysine acetylation is another type of posttranslational modification occurring in titin.doi:10.1152/japplphysiol.00617.2019Song HuangSujuan LiuYanmei NiuLi FuAmerican Physiological Society Bethesda, MD
In contrast to plants, mammalian O-glycosylation is a well understood posttranslational modification. Substitutions of serine and threonine residues with sugars such as fucose, galactose and N-acetylglucosamine are common modification on mammalian proteins [12], but the most abundant O-glycans in mammal...
In contrast to plants, mammalian O-glycosylation is a well understood posttranslational modification. Substitutions of serine and threonine residues with sugars such as fucose, galactose and N-acetylglucosamine are common modification on mammalian proteins [12], but the most abundant O-glycans in mammal...
regulation of gene expression, and complex pathology. To address these limitations, we optimized a hybrid protocol, ICuRuS, for the isolation of nuclei tagged in specific cell-types and histone post translational modification profiling from the striatum of a single mouse. We combined affinity-based ...
- 《Journal of Biological Chemistry》 被引量: 198发表: 1998年 Engineering mammalian mucin-type O-glycosylation in plants. Mucin-type O-glycosylation is an important post-translational modification that confers a variety of biological properties and functions to proteins. This ... Z Yang,DP Drew,...
Recently, it was revealed that the catalytic activity of PKM2 can be regulated by its posttranslational modification (PTM). Several PTM types, including phosphorylation, methylation, acetylation, oxidation, hydroxylation, succinylation, and glycylation, have been gradually identified on different amino ...
Neddylation, a type of protein post-translational modification similar to ubiquitination, regulates diverse biological processes by affecting subcellular localization, stability, and function of target proteins.7The role of neddylation in cancer cell biology has been extensively investigated with NAE-specific...
Accumulating evidence shows that the cytoplasmic tail of MT1-MMP is subjected to phosphorylation, and this post-translational modification regulates enzymatic activity at the cell surface. To investigate the potential role of MT1-MMP cytoplasmic residue Thr567 phosphorylation in regulation of metastasis-...
Post-translational modification Densities were observed in both EM maps that protrude into the solvent and cannot be attributed to the polypeptide backbone and were too large to account for amino acid sidechains (Fig.5a, b). These densities colocalised with serine residues and are similar in appea...