Changes in the abundance of α-PROTEIN post-translational modifications are of great significance in the study of life activities. Abnormal post-translational modifications can lead to the occurrence of a variety of diseases. Mass spectrometry can distinguish the changes in molecular weight of α-PROTE...
What are post-translation modifications of proteins? Learn types of post translational modifications that are made to the new proteins, such as phosphorylation, ubiquitylation, glycosylation, and cleavage, as well as post-translational modification examples. ...
Crucial events mediating the rapid modulation of cardiac titin stiffness are post-translational modifications (PTMs) of titin. In this review, we first recollect what is known from earlier and recent work on the molecular mechanisms of titin extensibility and force generation. The main goal then ...
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Glycosylation is an extremely common process that functions as both a co- and post-translational modification of proteins. 糖基化是一种极其常见的过程,可作为蛋白质的共翻译修饰和翻译后修饰。 Like many other protein modifications, glycosylation plays an important role in the regulation of a wide varie...
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S-palmitoylation is post-translational modification, which consists in the addition of a C16 acyl chain to cytosolic cysteines and which is unique amongst lipid modifications in that it is reversible. It can thus, like phosphorylation or ubiquitination, act as a switch. While palmitoylation of solu...
There is also the potential to miss modifications that would contribute to neoantigenic load, such as post-translational modifications. Regardless, continued research of both tumor and immune cells will help us further understand the c...
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