A non‐steady state dose‐response study was designed to quantitate peripheral sensitivity to insulin and pancreatic responsiveness to glucose, and to assess their relative contribution to glucose intolerance in Type 2 diabetes (Type 2 DM, non‐insulin‐dependent). Eleven lean and eleven obese patient...
Katzeff, H. L., Savage, P. J., Barclay-White, B., Nagulesparan, M. & Bennett, P. H. C-peptide measurement in the differentiation of type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus.Diabetologia28, 264–268 (1985). ...
Insulin use, disease complications raise costs in type 2 DMCost-analysisingentaconnectPharmacoEconomics and Outcomes News
Insulin action and resistance in obesity and noninsulin-dependent type II diabetes mellitus. Am. J. Physiol. 243 (Endocrinol. Metab. 6): E15-E30, ... JM Olefsky,OG Kolterman,JA Scarlett - 《Am J Physiol》 被引量: 926发表: 1982年 Oxidative stress and the etiology of insulin resistance...
Eliciting a type 2 response in the early stages of different cancers can be protective [138, 139]. This effect can be mediated through various mechanisms, including the recruitment of eosinophils in an IL-5-dependent manner [140, 141], TSLP-mediated Th2 polarization [138], and IL-4-...
Type 2 diabetes (T2D), which is characterized by low-grade inflammation, insulin resistance (Shoelson, 2006) and β-cell failure (Butler et al., 2003), has become increasingly prevalent worldwide (Xu et al., 2013). The estimated proportion of diabetes among adults is 8.3% in 2010, among...
Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid metabolism. Genetic, metabolic, multiple lifestyl...
Increased incidence of non–insulin-dependent diabetes mellitus among adolescents. J Pediatr. 1996;128(5, pt 1):608-615. doi:10.1016/S0022-3476(96)80124-7PubMedGoogle ScholarCrossref 17. Ball GD, Huang TT, Gower BA, et al. Longitudinal changes in insulin sensitivity, ...
Insulin-dependent diabetes affects testicular function by FSH- and LH-linked mechanisms. J Androl 2004; 25: 706–719. Article CAS Google Scholar Watson KE, Horowitz BN, Matson G . Lipid abnormalities in insulin resistant states. Rev Cardiovasc Med 2003; 4: 228–236. PubMed Google Scholar ...
et al. Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study. Am. J. Epidemiol. 145, 614–619 (1997). Article CAS PubMed Google Scholar Zheng, Y. et al. Associations of weight gain from early to middle adulthood with major health...