Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular complications (including retinopathy, nephropathy and neuropathy) and macrovas
–Alzheimer’s disease >. Scientific research has provided a strong evidence that insulin resistance and type 2 diabetes is the first step toAlzheimer’s– a form of dementia which has been found to be closely linked with type 2 diabetes. It explains why almostthree quarters of patients with ...
To investigate the relationship between diabetic foot complications (DFCs) and clinical characteristics, especially the number and types of first-degree family members with diabetes. A total of 8909 type 2 diabetes patients were enrolled. The clinical characteristics of these patients, including DFCs and...
Whether the relationship between type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) can be solely attributed to the shared risk factors, such as obesity, remains controversial. Several studies have revealed the critical role of abnormal glycosylation in the pathogenesis of OA and T2DM. Therefore...
People with diabetes require continuous self-monitoring and face numerous decisions in their day-to-day lives. Therefore, on many occasions, they need more support than that provided by health professionals. In this context, peer support in online diabetes communities could be a useful tool. The ...
The connection between type 2 diabetes and Parkinsons's in patients is previously known. A person with type 2 diabetes have a higher risk of also getting Parkinsons's disease, but not the other way round. But why? Proteins are the body's work horses and they are the molecular machines tha...
Gabriel J.Echeverri. (2010) Type 2 Diabetes Mellitus: Metabolic Surgery and Gastric Submucosal Islet Transplantation, Is There a Connection?. Transplantation 90 , 1036 /Echeverri GJ. Type 2 diabetes mellitus: metabolic surgery and gastric submucosal islet transplantation, is there a connection?
Aim: Cardiovascular diseases (CVD) are the leading cause of death globally. In the condition of type 2 diabetes mellitus (T2DM), the prevalence of CVD increase parallel with the rise of metabolic
We developed a deep-learning-based framework, multi-omics variational autoencoders (MOVE), to integrate such data and applied it to a cohort of 789 people with newly diagnosed type 2 diabetes with deep multi-omics phenotyping from the DIRECT consortium. Using in silico perturbations, we ...
We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites, lipids and proteins. Homocitrulline, isoleucine and 2-aminoadipic acid, eight triacylglycerol spec