According to NHS (2014), „A recent study has estimated that 35.3% of adults in the UK now have pre-diabetes (also known as borderline diabetes).” A country with one of the highest prevalences of diabetes is also America: „One in four Americans has either pre-diabetes or the full...
Mirkin has a wonderful way of making medical research & concepts easy to understand. This week he did an excellent job of explaining a very curious study published last week in JAMA that counter-intuitively found patients who were of normal weight at the time of their type-2 diabetes ...
Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. 1992. Int J Epidemiol 2013;42:1215-1222Hales CN, Barker DJP. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis, 1992 [ J ]. lnt J Epidemiol,2013,42(5 ) :1215 - 1222....
achieved may encourage either universal target setting, such as has been used to the detriment of many elderly patients in the UK [6], or self-serving ‘easy’ target setting in order to receive reward and recognition, rather than acting in the best interest of the person with diabetes. Nei...
To investigate the relationship between diabetic foot complications (DFCs) and clinical characteristics, especially the number and types of first-degree family members with diabetes. A total of 8909 type 2 diabetes patients were enrolled. The clinical ch
This paper describes the development of My Care Hub mobile phone application (app) aimed at supporting self-management in people with type 1 or type 2 diabetes. The development of My Care Hub involved a comprehensive process of healthy behavioural change identification, end users’ needs, expert ...
Our data unexpectedly show that glucose, which drives inflammation in other contexts, is dispensable for type 2 diabetes-associated inflammation. Instead, partial defects in the cell’s power plant, or mitochondria, fuel inflammation, but only in cells further stressed by the types of lipids that ...
Most research assessing the sensitivity to ischaemia–reperfusion injury has focused upon type 1 rather than type 2 diabetes [109]. Findings have often been conflicting, perhaps due to the differing methods of inducing diabetes, duration and severity of hyperglycaemia, animal models used, study protoc...
While Type 1 Diabetes Mellitus (T1DM) is characterized by hypoinsulinemia and hyperglycemia, persons with T1DM also develop insulin resistance. Recent studies have demonstrated that insulin resistance in T1DM is a primary mediator of the micro and macrov
Type 2 diabetes (T2D) affects approximately 425 million people worldwide and is projected to rise to 629 million by 2045, posing major health and economic consequences [1]. Gestational diabetes mellitus (GDM) history, as an independent T2D risk factor, confers a seven-fold risk of developing ...