1. Specificimmune responses induced by a hepatitis B virus preS2S DNA vaccine in BALB/c mice.; 乙肝病毒核酸疫苗诱导BALB/c小鼠特异性免疫应答 2. Herpesvirus entry mediator:a switch inimmune responseand its role in anti-tumor immunity;
Induction of type 1 immune responses against Bet v 1a allergens in mice by proteosome based mucosal adjuvantsChurg-Strauss syndromevasculitisasthmaasthma therapyleukotriene modifiersbeta-agonistcorticosteroidsforme frusteThe pulmonary vasculitides are a group of rare but serious disorders that require early ...
Two triple immunization vaccine regimens with adenoviral vectors with E1 deleted expressing Gag of human immunodeficiency virus type 1 were tested for induction of T- and B-cell-mediated-immune responses in mice and in nonhuman primates. The vaccine carriers were derived from distinct serotypes of ...
Type I interferons (IFNs) are potent mediators of the innate immune response against viruses and cancer. There are 16 members of the type I IFN family (IFNβ, IFNɛ, IFNκ, IFNω and 12 IFNα subtypes), which signal through the same receptor — composed of the subunits IFNAR1 and I...
Lessons from HIV-1 gene therapy in humanized mice: is targeting viral entry the road to success? Curr Gene Ther 16, 56–64, doi: 10.2174/1566523216666160104141644 (2016). 18. Brainard, D. M. et al. Induction of robust cellular and humoral virus-specific adaptive immune responses in human ...
1. Myocardial infarction activates IRF3-dependent signaling We hypothesized that the high levels of ischemic cell death during MI may disrupt DNA sequestration and liberate large quantities of self-DNA for cytosolic sensing, ultimately fueling a maladaptive IRF3- dependent innate immune response. To test...
Intact type 1 immunity and immune-associated coagulative responses in mice lacking IFN -inducible fibrinogen-like protein 2 喜欢 0 阅读量: 24 作者: W.,W.,Hancock,F.,M.,Szaba,K.,N.,Berggren,M.,A.,Parent,I.,K.,Mullarky,J.,Pearl,A.,M.,Cooper,K.,H.,Ely,D.,L.,Woodland,I.-J....
Rodent Models for Investigating the Dysregulation of Immune Responses in Type 1 Diabetes 来自 国家科技图书文献中心 喜欢 0 阅读量: 39 作者:FC Chou,HY Chen,SJ Chen,MC Fang,HK Sytwu 摘要: Type 1 diabetes (T1D) is an autoimmune disease mediated by T cells that selectively destroy the insulin...
astep function 阶梯函数[translate] aType 1 IFNs have many biological properties, including innate, cellular and humoral adaptive immune responses[41]. 第一类型IFNs有许多生物物产,包括固有,多孔和体液能适应的免疫反应(41)。[translate]
There is accumulating evidence that while acute type I IFN signaling improves immune responses prolonged stimulation leads to regulatory pathways, that limit immunity and promote chronic disease40. During chronic viral infections, bystander CD8+T cells exposed to IFNα are less able to proliferate upon...