Wedderburn LR, Woo P. Type 1 and type 2 immune response in children: their relevance in juvenile arthritis. Springer Semin Immunopathol 1999;21:361-74.Wedderburn LR, Woo P. Type 1 and type 2 immune responses in children: their relevance in juvenile arthritis. Springer Semin Immunopathol. ...
representative of TH1, type I IFN, TH17, and TH2 responses, hypothesizing that distinct responses underlying the immune response in each model could be determined by the transcriptional signature of unseparated lung cells. To this end, we have used bioinformatics...
传统观点认为,Type-1免疫反应是肿瘤免疫治疗的核心力量【1,2】而削弱Type-1免疫应答的Type-2免疫反应通常被视为促进肿瘤进展的因素【3】。以CAR-T细胞疗法和免疫检查抑制剂(Immune checkpoint inhibitor,ICB)为代表的免疫疗法均主要用于诱导Type-1免疫反应,并且在肿瘤治疗领域取得了革命性突破。这些创新疗法通过激活患者...
传统观点认为,Type-1免疫反应是肿瘤免疫治疗的核心力量【1,2】而削弱Type-1免疫应答的Type-2免疫反应通常被视为促进肿瘤进展的因素【3】。以CAR-T细胞疗法和免疫检查抑制剂(Immune checkpoint inhibitor,ICB)为代表的免疫疗法均主要用于诱导...
1. Specific immune responses induced by a hepatitis B virus preS2S DNA vaccine in BALB/c mice.; 乙肝病毒核酸疫苗诱导BALB/c小鼠特异性免疫应答 2. Herpesvirus entry mediator:a switch in immune response and its role in anti-tumor immunity; 疱疹病毒侵入介体在免疫应答及抗肿瘤免疫中的研究进展 3...
Both type I and type II IFNs regulate activation of the phosphatidylinositol 3-kinase (PI3K)-signalling pathway. One of the downstream effectors of PI3K is protein kinase C-δ, which functions as a serine kinase for STAT1. At least two distinct pathways for the regulation of mRNA translation...
aThe immune response to type II collagen and subsequent development of arthritis in rats is linked to the MHC RT1 locus andvaries with the species of type II collagen used for immunization. 对类型II胶原和随后发展的免疫反应关节炎在鼠与类型连接对MHC RT1所在地andvaries用于免役的II胶原的种类。 [...
American Society for Testing and Materials (ASTM), Type II immune responseASTM F1906-98(2003) Standard Practice for Evaluation of Immune Responses In Biocompatibility Testing Using ELISA Tests, Lymphocyte, Proliferation, and Cell Migration Others: Type 1 immunity and Type 2 immunity, Type 1 immunity...
(alternatively designated serotype g Streptococcussobrinus), including whole cells (WC g), cell walls (CW g), peptidoglycan (PG g) and serotype carbohydrate (Ml g) were coupled with trinitrophenyl (TNP), and the nature of the immune response to each immunogen was determined in normal and X-...
TANK-binding kinase 1 (TBK1) serves as a key convergence point in multiple innate immune signaling pathways. In response to receptor-mediated pathogen detection, TBK1 phosphorylation promotes production of pro-inflammatory cytokines and type I interferons. Increasingly, TBK1 dysregulation has been linked...