They defend your body against invading pathogens and also help it reap the benefits of vaccines. They are classified in several groups: B cells, T cells, and nonspecific effector cells. Let us consider one type of immune response, involving the work of the B cells.The World...
The Journal of Immunology, 2011, 187: 6473–6482. M icrobial infections are the most common cause of death in humans. While long-term protection frompathogens can be achieved by adaptive immune response, path- ogens are sensed by pathogen recognition receptors (PRRs) dur- ing the early ...
aThe immune response to type II collagen and subsequent development of arthritis in rats is linked to the MHC RT1 locus and varies with the species of type II collagen used for immunization. 对类型II胶原和随后发展的免疫反应关节炎在鼠连接对MHC RT1所在地并且随类型变化用于免役的II胶原的种类。[tra...
aThe immune response to type II collagen and subsequent development of arthritis in rats is linked to the MHC RT1 locus andvaries with the species of type II collagen used for immunization. 对类型II胶原和随后发展的免疫反应关节炎在鼠与类型连接对MHC RT1所在地andvaries用于免役的II胶原的种类。 [...
以CAR-T细胞疗法和免疫检查抑制剂(Immune checkpoint inhibitor,ICB)为代表的免疫疗法均主要用于诱导Type-1免疫反应,并且在肿瘤治疗领域取得了革命性突破。这些创新疗法通过激活患者自身的免疫系统,有效地识别并消灭癌细胞,为许多此前难以治疗的癌症患者带来了新的希望。靶向CD19的CAR-T疗法在复发/难治型B细胞急性淋巴...
以CAR-T细胞疗法和免疫检查抑制剂(Immune checkpoint inhibitor,ICB)为代表的免疫疗法均主要用于诱导Type-1免疫反应,并且在肿瘤治疗领域取得了革命性突破。这些创新疗法通过激活患者自身的免疫系统,有效地识别并消灭癌细胞,为许多此前难以治疗的...
Type I interferons (IFNs) are potent mediators of the innate immune response against viruses and cancer. There are 16 members of the type I IFN family (IFNβ, IFNɛ, IFNκ, IFNω and 12 IFNα subtypes), which signal through the same receptor — composed of the subunits IFNAR1 and ...
It is essential to explore the immune response characterist... Y Kang,S Lu,R Zhong,... - 《Heliyon》 被引量: 0发表: 2024年 Characterization of Patients With Type 2 Diabetes Mellitus and COVID-19 The coronavirus is a pathogen that mainly attacks the human respiratory system Previous ...
The type 2 immune response is critical for host defense against large parasites such as helminths. On the other hand, dysregulation of the type 2 immune response may cause immunopathological conditions, including asthma, atopic dermatitis, rhinitis, and anaphylaxis. Thus, a balanced type 2 immune...
aWhen the immune system is exposed again to the same type of antigen (or a similar one), these memory cells are activated, presenting a faster (and perhaps improved) response, which is called secondary response. 免疫系统被再次暴露到同样类型的抗原时 ( 或类似一个 ),这些记忆细胞被激活,存在快...