During the last decade, DNA-based immunization has been promoted as a new approach to prime specific humoral and cellular immune responses to protein antigens [8]. In mouse models, DNA vaccines have been successfully directed against a wide variety of tumors, almost exclusively by driving strong ...
Whether cooling was shallow or deep, rapid cooling attenuated the influence of cold exposure on the immune response. It is suggested that the differences in response to slow and rapid cooling could depend on the different responses of the skin cold receptors, the dynamic phase of the activity ...
another important white blood cell of the immune system, also play a part, specifically CD4+ or "helper" T cells that can initiate immune responses. Both B and T cells interact to control tuberculosis progression, but until this study, just how much either contributed and interacted wasn't co...
Macrophage migration inhibitory factor (MIF) is a mammalian cytokine that participates in innate and adaptive immune responses. Homologues of mammalian MIF... KD Augustijn,R Kleemann,J Thompson,... - 《Infection & Immunity》 被引量: 155发表: 2007年 Multistage multiantigen heterologous prime boost ...
Objective: To assess the immune effect of different types of hepatitis B vaccine (HepB) booster doses 2 to 32 years after primary immunization, explore the influencing factors, and offer guidance regarding the necessity and timing of boosters. Methods: In total, 1163 participants who were born ...
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. Inflammation plays an important role in the initiation and perpetuation of AF. The present study was conducted to characterize immune clusters in nonparoxysmal AF and
To compare the radiosensitivity of the different hematopoietic cell populations, we set out to determine the responses of different cell types obtained from peripheral blood of healthy volunteers in the same setting and under the same experimental conditions (without PHA or CD3/CD28 stimulation) of ly...
either not investigated individual variation in prebiotic response [40], or solely utilizedin vitroassays of prebiotic response [41,42]. If consistent evidence does emerge that responses to different prebiotics vary within people, then effective prebiotic therapies will face the challenging task of pers...
immune responses to non-spike viral proteins may provide additional protection when compared with animals immunized with spike-alone vaccines. Second, we did not analyze T cell and other types of immunity, which are known important for protection. Unlike neutraliztion that could be significantly evad...
The immunological engineered exosomes could elicit robust antitumor immunity. For example, fibroblast activation protein-α (FAP)-expressing exosomes, serving as tumor vaccine, could induce strong and specific cytotoxic T lymphocyte (CTL) immune responses against tumor cells and FAP+cancer-associated fibro...