Tunneling nanotubes (TNT): A potential mechanism for intercellular HIV trafficking. Commun Integr Biol 2009 ; 2:243 - 244 [Taylor & Francis Online] ,Eugenin E. A., Gaskill P. J., Berman J. W. (2009). Tunneling nanotubes (TNT): a potential mechanism for intercellular HIV trafficking ....
Fig. 1. Ultrastructure of tunneling nanotubes (TNTs). (A) Scanning electron microscopic (SEM) or (B) transmission electron microscopic (TEM) image of a TNT connecting two cultured PC12 cells. The boxed areas in (A) and (B) are shown as higher magnification images (insets A1–A3, B1,...
Tunneling nanotubes (TNTs), discovered in 2004, are thin, long protrusions between cells utilized for intercellular transfer and communication. These newly discovered structures have been demonstrated to play a crucial role in homeostasis, but also in the spreading of diseases, infections, and metasta...
Tumors are heterogeneous tissues that recruit non-cancerous cells to the tumor microenvironment. In the past few years, the paradigm for the intercellular communication within the tumor, mainly based on plasma membrane receptor signaling, radically changed with the discovery that cells can physically in...
Cell-to-cell communication coordinates the development of multicellular systems, and is mediated by soluble factors, gap junctions and the recently described tunneling nanotubes (TNT). Both TNT and gap junctions facilitate the transfer of intracellular mediators between the cytoplasm of connected cells. ...
Tunneling nanotubes (TNTs) represent a novel route of intercellular communication. While previous work has shown that TNTs facilitate the exchange of viral or prion proteins from infected to naïve cells, it is not clear whether the viral genome is als
Cell to cell communication is essential for the organization/coordination of multicellular systems and cellular development. Cellular communication is mediated by soluble factors, including growth factors, neurotransmitters, cytokines/chemokines, gap junctions, and the recently described tunneling nanotubes (TNT...
Tunneling nanotubes between rat primary astrocytes and C6 glioma cells alter proliferation potential of glioma cells Abstract The tunneling nanotube (TNT) is a newly discovered, long and thin tubular structure between cells. In this study, we established a co-culture system for rat primary astrocytes...
1Altmetric Metrics Abstract Cell-to-cell communication is essen for the development of multicellular systems and is coordinated by soluble factors, exosomes, gap junction (GJ) channels, and the recently described tunneling nanotubes (TNTs). We and others have demonstrated that TNT-like structures are...
Tunneling nanotubes (TNTs) are intercellular conduits which meet the communication needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred microns. TNTs are unique type of membrane protrusion which contain F-actin and freely hover over substratum in the extra...