pinealoma- tumor of the pineal gland plasmacytoma- neoplasm of plasma cells (usually in bone marrow) psammoma,sand tumor- a tumor derived from fibrous tissue of the meninges or choroid plexus or certain other structures associated with the brain; characterized by sandlike particles ...
BACKGROUND: Bone marrow stromal antigen 2 (BST-2) is a known anti-viral gene that has been recently identified to be overexpressed in many cancers, including breast cancer. BST-2 is critical for the invasiveness of breast cancer cells and the formation of metastasis in vivo. Although the reg...
(AMLs), there are some remnants of the old FAB classification, but new classifications were introduced for leukemias associated with consistently recurringchromosomal translocations. According to the WHO classification, a finding of at least 20% blasts in the bone marrow is required for diagnosis of ...
The whole body is trained to recognize things that do not belong there. This combination of what is called allergenicity cells from another person genetically modified the dendritic cell, then putting a piece of the tumor onto the dendritic cell, rather than guessing what the dendritic cell would...
a brain tumor composed of large, star-shaped cells called astrocytes. blastoma a neoplasm arising in the blastema, i.e., tissue from which an organ or part is formed. Alsoblastocytoma. cancericidal of or pertaining to a chemical or process than can destroy malignant cells. ...
In addition, the released angiogenic factors attract circulating bone marrow progenitor cells and stimulate their differentiation into ECs [19]. Then, new basement membrane is formed, and pericytes are attracted to circumvent the neo-vessel [20]. Apart from meeting the metabolic demands of the pre...
[42,43,44]. Additionally, even when a tumor antigen is shared with healthy cells, in hematological tumors it can be feasible to sacrifice the entire antigen-positive lineage to eradicate the cancer. This is because the intrinsic characteristic of the bone marrow tissue, that can be ablated, ...
The recent discovery of meningeallymphatic vessels(mLVs) called for reassessment of the historical concept that thecentral nervous system(CNS) entirely lacks alymphatic system.1,2mLVs exit the cranium along specificanatomical structuressuch as thesuperior sagittal sinus(SSS), thesinus sigmoideus(SS), ...
Metastasis, the spread of a tumor or cancer from the primary site of the body to a secondary site, is a multi-step process in cancer progression, accounting for various obstacles in cancer treatment and most cancer-related deaths. Metabolic reprogramming refers to adaptive metabolic changes that ...
␣41 is known to be involved in targeting different cell types to the bone marrow and bone (25, 26). We have, therefore, been successful in establishing an in vivo model for human Ewing tumor cells that recapitulates many aspects of the growth and progression pattern of Ewing tumors ...