The cell-line-derived subcutaneous tumor model in preclinical cancer researchdoi:10.1038/s41596-022-00709-3Stribbling, Stephen M.Ryan, Anderson J.Nature Protocols
The protocol leads to subcutaneous tumor growth usually within 1–3 weeks of cell injection and is suitable for those with experience in tissue culture and mouse experimentation. 展开 关键词: GROWTH-FACTOR HUMAN BREAST IN-VIVO ANTITUMOR-ACTIVITY XENOGRAFT MODELS PROSTATE-CANCER T-CELLS POTENT ...
The human melanoma cell line 1087-mel (provided by S.L. Topalian, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University) was cultured in RPMI-1640 medium supplemented with 10% FBS, 100 U/ml penicillin, 100 μg/ml streptomycin, 2 mM L-glutamine, 1 mM sodium pyruvate and non...
However, when cell suspensions of this tumor are injected intravenously, multiple lung foci develop. These foci were used as source for a cell subpopulation. Prolonged exposure of the original tumor cell line to increasing levels of lectins (concanavalin A and wheat germ agglutinin) resulted in ...
To determine whether the human hepatoblastoma cell line, HUH-6, secreted PEDF, serum-free CM were analyzed by immunoblot. Under normoxic conditions, the HUH-6 cells secreted PEDF as evidenced by the intense band at 50 kD (Fig. 1A, lane 2). However, when HUH-6 cell CM were collected in...
Exosomes are endosome-derived small membrane vesicles that are secreted by most cell types including tumor cells. Tumor-derived exosomes usually contain tumor antigens and have been used as a source of tumor antigens to stimulate anti-tumor immune respon
Tumor cell adhesion as a risk factor for sentinel lymph node metastasis in primary cutaneous melanoma J. Clin. Oncol., 33 (2015), pp. 2509-2515 Google Scholar 2 J.S. Desgrosellier, D.A. Cheresh Integrins in cancer: biological implications and therapeutic opportunities Nat. Rev. Cancer, 10...
We investigated whether these expanded NK cells may overcome the limitations of autologous NK cell therapy against solid tumors. Peripheral blood- and ascites-derived NK cells from ovarian cancer patients were expanded then adoptively transferred into cell-line and autologous patient-derived xenograft ...
Abstract 2647: Merestinib (LY2801653), targeting several oncokinases including NTRK1/2/3, shows potent anti-tumor effect in colorectal cell line- and patient-derived xenograft (PDX) model bearing TPM3-NTRK1 fusion 喜欢 0 阅读量: 23 作者:...
Dear Editor,Esophageal cancer(EC)is the sixth leading cause of death from cancer worldwide[1].It has remained a large burden in the world,especially in China[2].Esophageal squamous cell carcinoma(ESCC)is the major histological subtype of EC and is mostly regarded as a'silent'tumor in its ...