2015. Tumor suppressor p53 and its mutants in cancer metabolism. Cancer Lett 356:197-203.Liu J, Zhang C, Hu W, et al. Tumor suppressor p53 and its mutants in cancer metabolism. Cancer Lett. 2015;356(2 pt A):197-203.Liu J., et al. (2013). Tumor suppressor p53 and its mutants ...
The tumor suppressor p53 has been implicated in a growing number of biological processes, including cell cycle arrest, senescence, apoptosis, autophagy, me... M Farnebo,VJN Bykov,KG Wiman - 《Biochemical & Biophysical Research Communications》 被引量: 395发表: 2010年 p53 and metabolism: Inside...
Fibrosis is a reparative and progressive process characterized by abnormal extracellular matrix deposition, contributing to organ dysfunction in chronic diseases. The tumor suppressor p53 (p53), known for its regulatory roles in cell proliferation, apoptosis, aging, and metabolism across diverse tissues, ...
The p53 tumor suppressor protein is a transcription factor with sequence-specific DNA binding activity regulating gene expression related to multiple cellular functions including, but not limited to, cell cycle arrest, cell apoptosis, cell growth, DNA repair, cell metabolism, and the immune response ...
The meaning of TUMOR SUPPRESSOR GENE is any of a class of genes (such as p53) that act in normal cells to inhibit unrestrained cell division and that when inactivated (as by mutation) place the cell at increased risk for malignant proliferation. How to u
The p53 Tumor Suppressor Gene: From Molecular Biology to Clinical Investigation The tumor suppressor p53 is a phosphoprotein barely detectable in the nucleus of normal cells. Upon cellular stress, particularly that induced by DNA damage, p53 can arrest cell cycle progression, thus allowing the DNA ...
p53 is a key tumor suppressor that triggers cell cycle arrest, senescence, or apoptosis in response to cellular stress. Frequent p53 mutation in human tumors allows survival, sustained growth, and tumor progression. p53 is expressed at low levels under normal conditions, due to rapid protein turn...
large proportion of human kidney and breast carcinomas, suggesting that BTG2 is a tumor suppressor that links p53 and Rb pathways in human tumorigenesis... Boiko,Alexander,D.,... - 《Genes & Development》 被引量: 202发表: 2006年 Tumor suppressor p53 and its mutants in cancer metabolism He...
Tumor suppressor p53 and metabolism. J Mol Cell Biol. 2019;11(4):284–92. CAS PubMed Google Scholar Jiang P, Du W, Wang X, Mancuso A, Gao X, Wu M, Yang X. p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase. Nat Cell Biol. 2011;13(3):310...
p53(17-26)价格:￥1280/毫克产品详情:This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence ... 纯度:98% 包装规格:1mg 用途:科研 货号:CS10748 品牌:Chemstan 产地:中国 ...