Sarcomatoid carcinoma is a rare tumor with a poor prognosis, otherwise known as carcinosarcoma. Gastrointestinal origin is very rare and only a limited number of anal carcinosarcomas have been reported in the literature. The management of this rare cancer type is controversial. The aim of this...
while even a stratification byKRASorSTK11mutational status is not significant (p-value > 0.01, Fig.2b,c). The same was true for recurrence-free survival (RFS), with the only exception ofTP53which was found to be significantly associated with recurrence (p-value = 0.0053, log-rank...
Extrarenal rhabdoid tumor of the orbit is rare. We are aware of only 4 previously published cases5-8(Table 1). Orbital extrarenal rhabdoid tumor can occur in children and adults and can be seen as an intraconal or extraconal mass. One patient had a tumor involving the lacrimal gland that...
Isogenic clonal lineages enabled elucidation of pro-tumorigenic mechanisms associated with common copy number alterations, revealing Notch signaling potentiation as a driver of 1q gain in breast cancer. We propose that intrinsic, tissue-specific proliferative effects underlie tumor copy number patterns in ...
Background: Adenocarcinoma, not otherwise specified (ANOS), is a malignant salivary gland tumor that exhibits ductal differentiation but lacks any of the h... R Rajeev,VT Beena,K Choudhary,... - 《Oral Surgery》 被引量: 4发表: 2012年 加载更多来源...
Incidence of salivary gland tumors among atomic bomb survivors, 1950-1987. Evaluation of radiation-related risk. A wide-ranging search for benign and malignant tumors of the major and minor salivary glands among members of the Life Span Study sample of the Radiation E... CE Land,T Saku,Y Ha...
The evolution of CAR-T cell structure. There are five generations of CAR-T cells to date. scFv is currently the most commonly used targeting domain for CAR-T cells, and VHH is also emerging as a targeting domain for CAR-T cells with great potential. VH: heavy chain variable domain; VL...
” This means that the hormone-releasing tumor is growing in an abnormal place, such as the lungs or elsewhere. The tumors can be benign, but most frequently they are cancerous. Other causes of Cushing’s syndrome are benign tumors on the adrenal gland (adrenal adenomas) and less commonly,...
Despite physiological regulation, little is known about how tumor-derived factors disrupt normal MEP differentiation and cause erythrocytopenia and thrombocytosis. Aryl hydrocarbon receptor (AhR), a member of the basic helix-loop-helix family of transcription factors, plays an essential role in a wide...
UMAP of epithelial cells, colored by:atumor score;binferred CNV score;cthe number of mutations.dUMAP of epithelial cells. Clusters are labeled with inferred cell types. GMC basal gland mucous cell, PMC pit mucous cell, IM intestinal metaplasia.eScatter plot showing high correlations between the...