(A) HE staining shows that the tumor tissue is composed of epithelial cells and lymphoid stroma, with mixed granulomatous lesions, surrounded by normal salivary gland tissue. (B) The bilayered eosinophilic epithelial component forms glandular or cystic structures, with secretions within the lumina. (...
597 In 1976, Enzinger and Smith598“borrowed” the term HPC to describe a rather different-appearing soft-tissue tumor composed of ovoid to spindled cells arranged about a uniform branching vasculature. Subsequent ultrastructural and IHC studies of HPC, as defined by Enzinger and Smith, have ...
Cells capable of forming a neoplastic phenotype after acquiring genetic and epigenetic alterations will henceforth be referred to as “transformed cells”. Their clonal evolution is the result of a balance between intrinsic competency and extrinsic selective pressures, which is influenced by neighboring co...
a malignant glandular tumor of the soft tissues of the body. astroblastoma a malignant tumor that may invade the brain and spinal cord, especially investing blood vessels. astrocytoma a brain tumor composed of large, star-shaped cells called astrocytes. ...
19-15) when the stromal tissue extends into the glandular spaces and appears to be within them and pericanalicular when the regular round or oval glandular configuration of the glands is maintained. Often, both types of growth are present. The tubules are composed of cuboid or low columnar ...
When the epithelial lining is composed of a single layer of columnar nonciliated epithelial cells, the lesions have been classified as glandular papillomas. When combinations of squamous and glandular lining are seen, these lesions are designated mixed squamous and glandular papilloma. In the ...
of Spencer which was a neoplasm predominantly of adults22. The initial 11 cases of PPB were all large solid masses arising in the lung and/or pleura and were composed in part of embryonal-type rhabdomyosarcoma, nodules of chondrosarcoma, primitive spindle and small round cells with blastemal ...
One gap junction channel is composed of two hemi-channels from each interacting cell. One hemi-channel is formed by 6 connexin protein subunits and each connexin in turn features four transmembrane domains. Typically small molecules and second messenger such as cAMP and Ca2+-ions are transported ...
Edward J.EscottMD, inRadiologic Clinics of North America, 2013 Introduction The term head and neck cancer generally encompasses malignant neoplasms of soft tissue origin of the oral cavity, lips, nasal cavity, paranasal sinuses, pharynx, larynx, and salivary glands, as well as sarcomas arising in...
Neurofibroma: is composed of cells variously derived from Schwann cells, perineurial (fibroblastic) cells and fibroblasts. While these neoplasms therefore contain all of the cellular elements of a peripheral nerve sheath, the Schwann cell is still the likely primary cell. ...