The TRPM3 gene encodes a plethora of different proteins owing to alternative splicing and alternative exon usage. One site of alternative splicing affects the ion-conducting pore region and profoundly alters the pore properties of the encoded channels. The channels having the longer pore region ...
TRPM3 is the last identified member of the TRPM subfamily and is most closely related to TRPM1. Due to alternative splicing, the TRPM3 gene encodes a large number of different variants. One splice event, affecting the pore-forming region of the channel, changes its selectivity for divalent c...
Ensembl Gene IDENSG00000083067.25 Ensembl mRNA IDTRPM3-214 包装清单: 产品编号产品名称包装 QH52917SHuman TRPM3 qPCR Primer Pair1nmol each —说明书1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异。
Samuel, W., Jaworski, C., Postnikova, O.A., Kutty, R.K., Duncan, T., Tan, L.X., Poliakov, E., Lakkaraju, A., and Redmond, T.M. (2017). Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.Mol. Vis.23: ...
6h). To further investigate whether ATF4 has a direct transcriptional regulatory effect on the Trpm3 gene, we performed a luciferase reporter assay to determine the effects of ATF4 on Trpm3 promoter activity. The data showed that knockdown of ATF4 did not alter the luciferase activity of the ...
(miR-204) that is located within an intron of the TRPM3 gene (reminiscent of TRPM1 and miR-211) has been shown to underlie an inherited form of retinal dystrophy and ocular coloboma [83]. This gene-centric review focuses on the complex genomic organization, sequence variation, transcriptional...
Ensembl Gene IDENSMUSG00000052387.17 Ensembl mRNA IDTrpm3-222 包装清单: 产品编号产品名称包装 QM57766SMouse Trpm3 qPCR Primer Pair1nmol each —说明书1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异。
Human TRPM3 gene According to public genomic databases (e.g., National Center for Biotechnology Information, NCBI, Genome Reference Consortium Human Build 38 patch release 13, GRCh38.p13), the human TRPM3 gene (TRPM3) is one of the largest genes located on the long-arm of human chromosome...
The encoded protein mediates calcium entry, and this entry is potentiated by calcium store depletion.The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The ...
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store ...