结论 TPM1基因表达的抑制可能参与鼻咽癌的发生。%Objective To investigate the relation between TPM1 gene expression and nasopharyngeal carcinoma (NPC). Methods TPM1 expression was examined in three NPC cell lines (CNE1, CNE2 and 58F) and one nasopharyngeal epithelial cell line (NP69) by real ...
TPM1 抗原(重组蛋白) 中文名称: TPM1 抗原(重组蛋白) 英文名称: TPM1 Antigen (Recombinant Protein) 别名: CMH3; TMSA; CMD1Y; C15orf13; HTM-alpha 储存: 冷冻(-20℃) 相关类别: 抗原 概述 Full length fusion protein 技术规格 Full name: Synonyms: Swissprot: Gene Accession: Purity: Expression ...
并且整体文库更大的样本也会获得更多的reads,例如A样本测了1百万条reads,而B样本只测了一万条reads,显然单纯的将gene count作为表达量将会造成大量的基因在A样本中较B样本上调,这显然不是由于生物学因素造成的,而是由文库大小引入的。因此"gene count→gene expression"的转换需要充分地考虑到基因长度、文库大小等因素...
Dysregulated microglia, on the other hand, are associated with neurodegenerative diseases, yet the mechanisms underlying pro-inflammatory gene expression in microglia are incompletely understood. Methods:We investigated the role of the actin-associated protein tropomyosin 1 (TPM1) in regulating pro-...
介绍了不同的RNA-Seq标准化方法——RPKM/FPKM和TPM,并演示了如何从计数中计算这些值。最后会比较这几种算法, 视频播放量 768、弹幕量 0、点赞数 10、投硬币枚数 3、收藏人数 17、转发人数 5, 视频作者 小云爱生信, 作者简介 我司将持续更新生物信息学,相关视频,文章,关
1,RPKM, FPKM and TPM, clearly explained 2,What the FPKM? A review of RNA-Seq expression units 3,In RNA-Seq, 2 != 2: Between-sample normalization 4,RNA-Seq normalization explained 5,https://groups.google.com/forum/#!topic/rsem-users/IaZmviqghJc...
本研究通过WGCNA和差异基因表达分析来自肿瘤基因组图谱(The Cancer Genome Atlas,TCGA)数据库和基因表达综合(Gene Expression Omnibus, GEO)数据库的膀胱癌mRNA的表达数据,获得差异共表达基因。然后利用综合的生物信息学分析进行生物标志物挖掘,对利用数据挖...
If you have TPM data, you can simply manually log transform the gene expression matrix in the object@data slot before scaling the data. You have to replace your object@data slot with the desired gene expression matrix as follows: pbmc@data = log(x = norm + 1)) (分别来自github.com/sati...
MicroRNAs (miRNAs)2 are a class of naturally occurring small noncoding RNAs that regulate gene expression by targeting mRNAs for translational repression or cleavage (1, 2). Like protein-coding mRNAs, miRNAs are transcribed as long primary transcripts in the nucleus. However, unlike protein-coding...
导语GUIDE ╲ GEPIA (Gene Expression Profiling Interactive Analysis) web服务器是2017年推出的,是基于TCGA和GTEx数据库中肿瘤和正常样本进行基因表达分析的一个资源...数据库介绍 GEPIA2具有198 619种isoforms(功能上相似的蛋白质,具有相似但不完全相同的氨基酸序列,由不同基因编码,或由去除不同外显子的相同基因的...