Congenital stationary night blindness (CSNB) is a disease affecting the night vision of individuals. Previous studies identifiedas a gene involved in reduced night vision. Homozygous deletion ofwas the cause of CSNB in several children in 6 Ashkenazi Jewish families, thereby prompting further ...
Gene Symbol TRPM1 Gene ID (NCBI) 4308 RRID AB_2881269 Conjugate Unconjugated Form Liquid Purification Method Antigen affinity purification UNIPROT ID Q7Z4N2 Storage Buffer 0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for...
Finally, we showed that detailed electroretinography is an effective way to discriminate among patients with mutations in either TRPM1 or GRM6, another autosomal-recessive cCSNB disease gene. These results add to the growing importance of the diverse group of TRP channels in human disease and ...
11 Because of the downregulation of TRPM1 in Appaloosa horses with CSNB, it was suggested that this gene may play a role in neural transmission in the human retina through changing cytosolic-free Ca2+ levels in the retina in ON bipolar cells. The mGluR6 protein (MIM 604096) of the ON ...
Gene SummaryEnables cation channel activity. Involved in cellular response to light stimulus. Acts upstream of or within cellular protein localization; retinal rod cell development; and signal transduction. Located in new growing cell tip. Is expressed in foregut; reproductive system; and sensory organ...
Ensembl Gene ID ENSMUSG00000030523.19 Ensembl mRNA ID Trpm1-201 包装清单: 产品编号 产品名称 包装 QM17042S Mouse Trpm1 qPCR Primer Pair 1nmol each — 说明书 1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所...
为确定TRPM1在不同发育阶段不同毛色绵羊皮肤中的表达与定位，并探讨其在调控绵羊毛色形成中的作用机制。运用实时荧光定量PCR（qRT-PCR）、Western Bloting、免疫组化技术分别检测不同发育阶段不同毛色绵羊皮肤中TRPM1的表达与定位。结果表明，不同月龄的杂交黑白公绵羊中TRPM1 mRNA均有不同程度的表达：在白色绵羊...
Outside the retina, two splice variants of TRPM1 regulate pigmentation in melanocytes, and loss of this gene is correlated with tumor aggressiveness in human melanoma19–21. ptbryaatnacWnshfheaccclioltteeisvdetehdTeGtrRheαPei oMsc, hos1tarrnioannnftergole,eeCbvGHuidtβOea γnpc ...
The protein encoded by this gene is similar to the transient receptor potential (Trp) calcium channel family members. The expression of this protein is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis. ...
The protein encoded by this gene is similar to the transient receptor potential (Trp) calcium channel family members. The expression of this protein is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis. 仅用于科研。不用于诊断过程。未经明确授权不得转售。