来源期刊 Dissertations & Theses - Gradworks 2012 研究点推荐 CD4+ T cell mediated tumor immunity cancer immunotherapies cancer immunotherapy hematopoietic stem cells TRP-1 TCR gene TRP-1 TCR gene modified hematopoietic stem cells 辅助模式 0 引用 文献可以批量引用啦~欢迎点我试用!
13,16 Previous study has revealed that TRPV1 is functionally expressed in CD4+ T cells and promotes the activation and pro-inflammatory properties of CD4+ T cells.14 The wide distribution of TRPV1 in immune cells suggests its role in modulating inflammatory responses. However, the reported ...
Immunology CD4+ T cell mediated tumor immunity following transplantation of TRP-1 TCR gene modified hematopoietic stem cells INDIANA UNIVERSITY Christopher E. Touloukian HaSung PilImmunotherapy for cancer has held much promise as a potent modality of cancer treatment. The ability to selectively destroy...
Pre-clinical validation of SmartDC-TRP2 in melanoma patients (n=5). Human SmartDC-TRP2 generated from CD14+monocytes from melanoma patients show DC immunophenotye and are potential stimulators of T cells. CD14+monocytes were isolated from PBMNCs of melanoma patients, preconditioned with cytokines...
T-cell tumors from Vav1-P53CKO mice derive from thymic T-cell progenitors. (A) Classification of T-cell lymphomas by expression of CD4 and CD8 on the cell surface.DPdouble positive andDNdouble negative (n=19) DP+CD8+ refers to lymphomas having a mixture of DP+ cells and CD8 SP+ cells...
Interestingly, the clone 37 TcR transgenic (Tg) mice did not develop autoimmune depigmentation despite the presence of TRP-2-reactive T cells in the lymph nodes and systemic expression of TRP-2. These Tg T cells displayed a naïve phenotype (CD44low, CD62hi, CD69neg, and CD25neg) and ...