【我的口译关键词:Trop-2】Trophoblast cell surface antigen-2 (Trop-2) is a widely expressed glycoprotein on a variety of different tumours. Trop-2 is considered as a marker of germ cells and is associated with regenerative ability in several tissues. Some studies demonstrated both oncogenic and...
Trop-2全称为人滋养细胞表面抗原2(Trophoblast Cell-Surface Antigen 2 ),其实Trop-2在一众靶点之中算得上是“老面孔”了,1990年前后就被科研人员成功分离。 而后,科学家们发现,Trop-2主要有两种功能:首先,它作为一种跨膜糖蛋白,参与细胞粘附。除此之外,它还能通过促进钙从内质网流出,使细胞增殖通路磷酸化,参与...
Trophoblast cell surface antigen 2 (Trop-2) is a transmembrane glycoprotein that is involved in a variety of oncogenic cell signaling pathways. Its potential as a target for the antibody鈥揹rug conjugate sacituzumab govitecan has already been demonstrated in different tumor entities. The United ...
Trophoblast cell-surface antigen 2 (TROP2) is related to tumor proliferation enhancement and poor prognosis. An antibody targeting TROP2 was developed to treat metastatic triple-negative breast cancer (TNBC) which has a limited treatment modality. To characterize the TROP2 expressing tumors in TNBC,...
Since a pretargeting method relies on the retention of the bispecific antibody on the cell surface, there was concern that an internalizing anti-TROP-2 antibody would not be an ideal first targeting agent because of a short residence time on the tumor cell surface. However, even after a ...
Trophoblast cell surface antigen 2 (Trop-2) belongs to the family of tumor-associated calcium signal transducer ( TACSTD ) and is required for the stability of claudin-7 and claudin-1, which are often dysregulated or lost in carcinogenesis. Here, we investigated the effects of Trop-2 ...
Global TROP2 (Trophoblast Cell-surface Antigen 2) Targeted Cancer Therapy Market- (By Application (Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Pancreatic Cancer, and Others)),
Trophoblast cell surface antigen 2 (TROP2) is highly expressed in various human malignant tumours; however, this has not been demonstrated clearly in EOC. In this study, we further evaluated whether TROP2 is a promising marker for EOC, and thus also a potential target for EOC immunotherapy. ...
中文名称: 人滋养层细胞表面抗原2(TROP-2)ELISA试剂盒 中文同义词: 人滋养层细胞表面抗原2(TROP-2)ELISA试剂盒 英文名称: Human trophoblast cell surface antigen 2 (TROP-2) ELISA kit 英文同义词: CAS号: 分子式: 分子量: 0 EINECS号: 信息错误报告 您的Email: 按...
Human trophoblast cell-surface marker (Trop-2) is a surface glycoprotein originally identified in human placental tissue and subsequently found to be highly expressed by various types of human epithelial solid tumors. We investigated the efficacy of saci