amino acids on the tRNA,which is catalyzed by a group of tRNA-dependent modifying enzymes,such as tRNA-dependent amidotransferases,Sep-tRNA:Cys-tRNA synthase,O-phosphoseryi-tRNA kinase and Sep-tRNA:Sec-tRNA synthase.The majority of these indirect pathways are widely spread in all domains of ...
6. Battaglia, R.A., Grigg, J.C. & Ke, A. Structural basis for tRNA decoding and aminoacylation sensing by T-box riboregulators.Nat Struct Mol Biol(2019). 7. Grigg, J.C. & Ke, A. Structural Determinants for ...
Amino acid signalingAminoacyl-tRNA synthetaseAminoacyl-tRNA synthetases (ARSs) are a family of evolutionarily conserved housekeeping enzymes used for protein synthesis that have pivotal roles in the ligation of tRNA with their cognate amino acids. Recent advances in the structural and functional studies ...
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et al. Pol III binding in six mammals shows conservation among amino acid isotypes despite divergence among tRNA genes. Nat. Genet. 43, 948–955 (2011). CAS PubMed PubMed Central Google Scholar Gogakos, T. et al. Characterizing expression and processing of precursor and mature human tRNAs...
and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. Alanyl-tRNA ...
tRNA与mRNA是通过反密码子与密码子相互作用而发生关系的. 18648 AA-tRNA即是氨基酰-tRNA 是的.AA:Amino Acid,氨基酸.AA-tRNA,即携带有氨基酸的tRNA,是氨酰tRNA的简写. 18648 tRNA的二级结构和主要功能 三叶草型,主要运输氨基酸并与mRNA进行配对,在翻译中起重要作用 18648...
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1. ...
5. Myung Hee Park, et al. Hypusine, a polyamine-derived amino acid critical for eukaryotic translation. J Biol Chem. 2018 Nov 30; 293(48): 18710–18718.6. Jie Zhou, et al. How the Ribosome Hands the A-site tRNA to the P Site During EF-G-catalyzed Translocation. Science. 2014 Sep...