In conclusion, tRF-Glu-CTC expression is increased after vascular injury and inhibits FMOD expression in VSMCs, which influences neointima formation. On the other hand, reducing the expression of tRF-Glu-CTC after vascular injury may be a potential approach to prevent vascular ...
To validate the specificity of tRF-GluCTC as a potential biomarker for liver metastasis, we compared its expression in PDAC patients with or without liver metastases. Using RT-qPCR on peripheral blood exosomes, we detected the expression of 4 candidate tRFs in 5 PDAC patients with liver metastase...
Transfer RNA derived fragment, tRF-Glu-CTC, aggravates the development of neovascular age-related macular degenerationdoi:10.7150/thno.92943Yu LiangLingjie KongYuelu ZhangYihan ZhangMingsu ShiJiaqiu HuangHongyu KongSiyi QiYunlong YangJiaxu HongTheranostics...
The tRF-GluCTC-0005 in PDAC-exo significantly recruits myeloid-derived suppressor cells (MDSCs) in the liver, creating a PMNs immunosuppressive microenvironment and further advancing liver metastasis from PDAC. Our results suggest that the key of PDAC liver metastasis is the activation of HSCs ...
Circulatory exosomal tRF-Glu-CTC-005 and tRF-Gly-GCC-002 serve as predictive factors of successful microdissection testicular sperm extraction in patients with nonobstructive azoospermia - ScienceDirectQiang Zhang Ph.D. aZhao Liu M.S. fXiaoxiao Han M.D. g...