In vitro, tRF-Glu-CTC inhibited the expression of fibromodulin (FMOD) in VSMCs, which is a negative modulator of TGF-尾1 activity. tRF-Glu-CTC also increased VSMC proliferation and migration. In vivo experiments showed that inhibition of tRF-Glu-CTC expression after ball...
To assess the prognostic value of tRF-GluCTC, we performed a Kaplan-Meier survival analysis. Patients with high tRF-GluCTC levels exhibited significantly shorter overall survival (OS) and disease-free survival (DFS) compared with low tRF-GluCTC levels in both cohort I (n = 73) and coho...
tRNA来源的小RNA(tRF)的生物学功能及在癌症中的作用
tiRNA-5030-GlnTTG-3, tiRNA-5029-GlyGCC-3, tiRNA-5035-GluTTC-1, tiRNA-5035-GluTTC-2, tiRNA-5034-GluTTC-2, tiRNA-5035-GluTTC-3, tiRNA-5032-GluTTC-1, tiRNA-5035-GluCTC, tiRNA-5030-SerGCT-3, tiRNA-5030-SerGCT-1, tiRNA-5031-HisGTG-2, tiRNA-5029-AlaAGC-1, tiRNA-5032-LysCTT-1...
Arraystar公司推出的nrStar™ Human tRF & tiRNA PCR Array包含了185类来自权威数据库收录和最新文献报道的tRF或tiRNA,方便客户对tRF & tiRNA进行简单快捷地表达谱分析。
Transfer RNA derived fragment, tRF-Glu-CTC, aggravates the development of neovascular age-related macular degenerationdoi:10.7150/thno.92943Yu LiangLingjie KongYuelu ZhangYihan ZhangMingsu ShiJiaqiu HuangHongyu KongSiyi QiYunlong YangJiaxu HongTheranostics...
The tRF-GluCTC-0005 in PDAC-exo significantly recruits myeloid-derived suppressor cells (MDSCs) in the liver, creating a PMNs immunosuppressive microenvironment and further advancing liver metastasis from PDAC. Our results suggest that the key of PDAC liver metastasis is the activation of HSCs ...
Circulatory exosomal tRF-Glu-CTC-005 and tRF-Gly-GCC-002 serve as predictive factors of successful microdissection testicular sperm extraction in patients with nonobstructive azoospermia - ScienceDirectQiang Zhang Ph.D. aZhao Liu M.S. fXiaoxiao Han M.D. g...