HCQ has a good safety profile and favorable results in terms of controlling clinical manifestations in SLE. In addition to known side effects such as retinal toxicity and neuromusculopathy, prolongation of the QT interval is mentioned in multiple studies. The QT interval can be prolonge...
Droperidol and ondansetron have previously been found to prolong the QT interval in the treatment of postoperative nausea and vomiting. However, this adver... Beny,Charbit,Jean,... - 《Anesthesiology》 被引量: 163发表: 2008年 The additive interactions between ondansetron and droperidol for preventin...
Finally, the World Health Organization (WHO) announced a "drug alert" on halofantrine advising a change in recommendations for its use. In the present paper, we discuss the first Japanese vivax malaria patient whose QT interval was prolonged after treatment with halofantrine. 展开 ...
The QT interval is just one important determinant of the risk of TdP and other risk factors should also be taken into account when planning patient management. In aLQTS the arrhythmia is more likely to occur in those with bradycardias or pauses because impairment of IKr produces a prolonged an...
who often have abnormal sinus node dysfunction, tachyarrhythmia (sinus tachycardia, supraventricular tachycardia and atrial fibrillation), conduction abnormalities (right bundle branch block and intraventricular block), prolonged QT interval, and nonspecific changes in the ST segment. A small number of patie...
Common adverse events included HLS, APL differentiation syndrome, a prolonged QT interval on electrocardiography, skin rash, and hyperglycemia. The occurrence of some toxic events including gastrointestinal disturbance, facial edema, and cardiac toxicity seemed less severe in the group given low-dose As2...
is a well-described consequence of sustained arterial hypertension.13 Even small, non-specific abnormalities of repolarization may increase the risk of cardiovascular events in the hypertensive population.14 In subjects with uncomplicated hypertension, a prolonged QT interval (corrected for heart rate) car...
24 h in patients with HS, who often have abnormal sinus node dysfunction, tachyarrhythmia (sinus tachycardia, supraventricular tachycardia and atrial fibrillation), conduction abnormalities (right bundle branch block and intraventricular block), prolonged QT interval, and nonspecific changes in the ST ...
A 75-year-old woman presenting with pre-syncope, shortness of breath and nausea was admitted to the emergency department following treatment with clarithromycin. Shortly after admission she developed a prolonged QT interval leading to torsades de pointes (TdP) and cardiac arrest. She was successfully...
such as thrombocytopenia, anemia, neutropenia or febrile neutropenia, while gastrointestinal (diarrhea, vomiting, increased alanine aminotransferase or aspartate aminotransferase levels), cardiological (prolongation of QT interval), pulmonological (pneumonia) and dermatological (rash) complications occurred less...