It is very important to understand what neoplasia is affecting the CNS in these cases in order to provide owners with the prognosis and the best therapeutic or palliative option. CNS lymphoma is definitely one of the most aggressivetumours affecting small animals, but is sometimes ove...
The frequency of central nervous system (CNS) dissemination in non-Hodgkin’s lymphoma (NHL) varies and is dependent on NHL histology. More than 50% of patients with CNS involvement have advanced and progressive systemic disease. While CNS involvement at initial diagnosis may be treated curatively...
Green MR, Chowdhary S, Lombardi KM, Chalmers LM, Chamberlain M (2006) Clinical utility and pharmacology of high-dose methotrexate in the treatment of primary CNS lymphoma. Expert Rev Neurother 6(5):635–652. : 10.1586/14737175.6.5.635...
Cancers of the brain are the consequence of abnormal growths of cells in the brain. Brain cancers can arise from primary brain cells, the cells that form other brain components (for example, membranes, blood vessels), or from the growth ofcancercells that develop in other organs and that ha...
Specifically a method of treating a CNS malignancy in a subject comprising administering to said subject, a therapeutically effective amount of a BTK inhibitor of Formula (A1) is provided, wherein the preferred CNS malignancy is glioblastoma multiforme or CNS lymphoma.SUKBUNTHERNG, Juthamas...
The cancer risk is most dramatic for blood cancers, such as leukemia and lymphoma, but is also increased for breast cancer. This risk probably relates, in part, to the altered immune system that is characteristic of SLE. Women with SLE appear to be at increased risk for heart disease (...
Ungerechts G, Springfeld C, Frenzke ME, Lampe J, Johnston PB, Parker WB, Sorscher EJ, Cattaneo R: Lymphoma chemovirotherapy: CD20-targeted and convertase-armed measles virus can synergize with fludarabine. Cancer Res. 2007, 67 (22): 10939-10947. 10.1158/0008-5472.CAN-07-1252. Article ...
lymphoma or inflammatory lesions are suspected. Alternative pharmacological measures, such as osmotic agents, are rarely necessary. Patients who have suffered epileptic seizures should receive anticonvulsant drugs preoperatively. Primary prophylaxis does not reduce the risk of a first seizure in patients ...
The use of radiotherapy alone to treat primary central nervous system lymphoma (PCNSL) does not produce the high local control and survival rates that it does in limited extranodal non-Hodgkin's lymphoma outside the central nervous system (CNS). Even with doses of whole brain radiation therapy...
Diagnose some blood cancers, such as leukemia and lymphoma. Find out if cancer has invaded the bone marrow. Look how a person's body handles cancer treatment. Diagnose other noncancerous conditions. The results of CBC are interpreted as: Low white blood cell count: Cancer treatment tends to ...