The article offers information on primary amyloidosis (AL) which is caused by the deposition of monoclonal immunoglobulin light chains occurring in patients with some form of clonal plasma-cell dyscrasias. It highlights ...
Primary (AL, amyloid light-chain) amyloidosis is a plasma cell disorder in which deposits of amyloid light-chain protein cause progressive organ failure. It is important to recognise that amyloidosis is a dynamic process and chemotherapy-induced reduction of the activity of the plasma cell clone re...
The Successful Treatment of Primary Amyloidosis with Intermittent Chemotherapy Summary: The successful treatment of primary amyloidosis with intermittent chemotherapy. K Bradstock,R Clancy,J Uther,... - 《Australian & New Zealand Journal of Medicine》...
The authors provide instruction on all forms of amyloidosis - including primary amyloidosis (AL), secondary amyloidosis (AA), and familial amyloidosis. With essential treatment algorithms, Amyloidosis: Diagnosis and Treatment is the gold-standard for all hematologists, oncologists, and internists caring...
Amyloidosis, disease characterized by the deposition of an abnormal protein called amyloid in the connective tissues and organs of the body that inhibits normal functioning. Amyloid is a fibrous, insoluble protein-carbohydrate complex that forms when nor
Primary amyloidosis of the conjunctiva and eyelid is a rare and often misdiagnosed condition. It is characterized by the deposition of insoluble amyloid fi... A Amir,B Amir,R Rabah,... - 《Journal of Surgical Case Reports》 被引量: 0发表: 2024年 加载更多研究...
Chemotherapy and/or bone marrow transplant may be highly effective for patients with primary amyloidosis that accompanies a form of bone marrow cancer called multiple myeloma. A bone marrow transplant is a procedure in which a patient's own bone marrow, which is often the source of amyloid ...
Primary or AL amyloidosis results from a plasma cell dyscrasia in which fibrillar light chain protein deposition leads to organ failure and death. Standard treatment for AL amyloidosis has been oral melphalan and prednisone. However, this form of treatment modifies the natural history of this ...
AL amyloidosis (immunoglobulin light chain amyloidosis).This is the most common type and used to be called primary amyloidosis. AL stands for "amyloid light chains," which is the type of protein responsible for the condition. There’s no known cause, but it happens when your bone marrow makes...
Light-chain amyloidosis—also called primary amyloidosis—is the most common type and accounts for 70% of amyloidosis cases.13It causes amyloid proteins to be overproduced in the bone marrow by plasma cells, a type of white blood cell that produces antibodies. In this type, the amyloid protein...