Q: What are the different types of amyloidosis and what treatment options are available?Carli Greenfield, ACNP
Your doctor will do a genetic test if they think you have a type that is passed down through families. Treatment for hereditary amyloidosis differs from that for other types of the disease. Once you’re diagnosed, your doctor might check your heart with anechocardiogramor your liver and spleen...
The underlying inflammatory driver of her AA amyloidosis was never identified and given that she had migrated some years earlier from Africa, previous chronic infection that has resolved or responded to non-disclosed prior treatment was thought to be the most likely cause. Whether the subsequent ...
Swelling or enlargement of the tongue, referred to as macroglossia, can be caused by allergies, medications, injuries, or an underlying medical condition such as amyloidosis. Addressing the underlying condition is the usual treatment for macroglossia. Allergic reactions to medications, food, or even...
Disorders of connective tissue Muscular dystrophies Autoimmune disease Infections of the heart muscle Infiltrative diseases ( hemochromatosis , sarcoidosis , or amyloidosis ) Endocrine disorders ( thyroid conditions, diabetes ) Chronic substance use disorder (especially alcohol or cocaine ) Pregnancy Morpho...
In the 5xFAD mouse model of amyloidosis and double mutant K257T/P301S mouse model of tauopathy (DMhTAU), senescent microglia displayed a protein signature distinctive from DAM, including canonical senescence-related proteins, homeostatic microglial markers, and elevated levels of apolipoprotein E (...
Inflammatory and autoimmune diseasesthat may affect brain function includesarcoidosis,amyloidosis,inflammatory bowel disease, andrheumatoid arthritis. Some of the brain damage may be caused by inflammation of the blood vessels in the brain, which causesstrokes. ...
Two of them had a normal HRCT, and the remaining three proved to have an infection. Another 16 patients with abnormal chest radiographs were excluded because of heart failure (n=5), infection (n=9), carcinoid tumor, or amyloidosis with bilateral radiological infiltration. The radiologist (J.B...
Information about cardiomyopathy, a disease of the heart muscle. The most common symptoms include shortness of breath, chest pain, and fatigue. There are several causes of cardiomyopathy. Types, diagnosis, treatment, and prognosis information is provided
M. Human brain pericytes as a model system to study the pathogenesis of cerebrovascular amyloidosis in Alzheimer’s disease. Cell Mol Biol 45, 37–46 (1999). PubMed CAS Google Scholar Lazcano, Z. et al. Unilateral injection of Aβ25-35 in the hippocampus reduces the number of dendritic...