The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β‐thalassemia major in China, including its epidemiology and treatment....
Pulmonary hypertension in beta-thalassemia major and the role of L-carnitine therapy. Cardiac complications, such as pulmonary hypertension (PHT), are the leading cause of death in beta-thalassemia patients. L-Carnitine, due to its role in f......
β-Thalassemia is one of the most common inherited anemias, with no effective cure for most patients. The pathophysiology reflects an imbalance between α- and β-globin chains with an excess of free α-globin chains causing ineffective erythropoiesis an
Role of Thalidomide in Treatment of Beta Thalassemia 来自 ResearchGate 喜欢 0 阅读量: 13 作者:V Ramanan,K Kelkar 摘要: Thalidomide is a fetal hemoglobin inducer. So this could be used to gain transfusion independence in Thalassemia Major and Thalassemia Intermedia along...
Dr. Neel recognized that the parents of children with thalassemia major had thalassemia minor with one beta thalassemia gene. When these parents had children, they had a 25% chance of having a thalassemia major child (with both genes for beta thalassemia), a 50% chance of having children with...
Dr. Neel recognized that the parents of children with thalassemia major had thalassemia minor with one beta thalassemia gene. When these parents had children, they had a 25% chance of having a thalassemia major child (with both genes for beta thalassemia), a 50% chance of having children with...
2. Early Results of a Phase I/II Study of Gene Therapy for beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex-Vivo with a Lentiviral beta(AT87Q)-Globin Vector [J] . Soni Sandeep, Thompson Alexis A., Walters Mark, Biology of blood and marrow tra...
Augmentedlevels of fetal hemoglobin (HbF) can revolutionize the severity of the β-hemoglobin disorders, like β-thalassemia.More recently, major advances have been made in the discovery of critical modifier genes, such as BCL11A (Bcell lymphoma 11A), a master regulator of HbF (fetal hemoglobin...
What are the Symptoms of Thalassemia? What is Cooley's Anemia? What is Beta Thalassemia? Discussion Comments Byanon924986— On Jan 09, 2014 A splenectomy is one of the best alternative solution for thalassemia major? How often does it work?
Endocrinopathies in beta thalassemia: a narrative review Article 16 December 2023 References Fessas P, Loukopoulos D. The beta-thalassaemias. Clin Haematol 1974; 3: 411–35 Google Scholar Wonke B. Management of beta-thalassaemia major. Curr Paediatr 1994; 4: 38–42 Article Google Scholar...