This evidence also shows that these elements have been active in DNA-mediated transposition at some point in the mammalian lineage. Therefore, it appears that the process of DNA-mediated transposition has occurred in mammalian cells and that its maximal cis -requirements are contained in the 80 ...
We have identified in the human genome two families of mobile elements possessing the sequence characteristics of transposons that move directly from DNA to DNA rather than requiring the reverse transcription of an RNA intermediate. One type of element is closely related to the autonomous transposable...
4. the movement of a gene or set of genes from one DNA site to another. [1530–40; < Medieval Latin trānspositiō. See trans-, position] trans`po•si′tion•al, trans•pos′i•tive (-ˈpɒz ɪ tɪv) adj. Random House Kernerman Webster's College Dictionary, © ...
DNA Transposition by the RAG1 and RAG2 Proteins : A Possible Source of Oncogenic Translocations Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage...
Structure–function insights into the initial step of DNA integration by a CRISPR–Cas–Transposon complex Ning Jia Wei Xie Dinshaw J. Patel CorrespondenceOpen Access10 Jan 2020Cell Research Volume: 30, P: 182-184 Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR...
DNA transposition are the MuA(andB) gene products,E. colihistone-like protein HU, Mg2+, ATP, a supercoiled ‘donor’ plasmid containing the left and right ends of Mu in the proper orientation, and a target DNA molecule.The DNA sequences at the Mu left and right ends contain three ...
Noun1.transposon- a segment of DNA that can become integrated at many different sites along a chromosome (especially a segment of bacterial DNA that can be translocated as a whole) jumping gene deoxyribonucleic acid,desoxyribonucleic acid,DNA- (biochemistry) a long linear polymer found in the nu...
function.The amount of total genomic DNA varies widely between organisms, and the proportion of coding and noncoding DNA within these genomes varies greatly... Cvalue - 《Noncoding Dna》 被引量: 738发表: 2001年 加载更多研究点推荐 Alu Retrotransposition-Mediated Genomic Variation Retrotransposons re...
Thus, we suggest that Tn7 transposition occurs in a nucleoprotein complex containing several proteins and the substrate DNAs and that recognition of attTn7 within this complex provokes strand cleavages at the Tn7 ends. 展开 关键词: Cell-Free System Chromosomes, Bacterial Escherichia coli Adenosine...
Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394: 744–751. CrossRef Ajioka, J.W. & D.L. Hartl, 1989. Population dynamics of transposable elements, pp. 939–958 in Mobile DNA, edited by D.E. Berg and M.M. Howe. ...