The roles of transmembrane proteins in living cells are diverse. They are involved in the transport of various solutes and information through membranes, in energy production, in metabolism and more. Despite their biological importance, the number of their structures in Protein Data Base is rather ...
Computer science Transmembrane Protein Prediction using Support Vector Machines UNIVERSITY OF CALIFORNIAIRVINE Pierre F. Baldi ShivaramKiranTransmembrane (TM) proteins are an important family of proteins, responsible for key biological functions. Understanding their structure and properties has proved to be ...
We conclude that cautious applications of AlphaFold2 structural models will advance TM protein-associated studies at an unexpected level. 展开 关键词: Structure prediction Transmembrane proteins AlphaFold2 Bioinformatics DOI: 10.1007/s00018-021-04112-1 年份: 2022 ...
Mem Brain: An Easy-to-Use Online Webserver for Transmembrane Protein Structure Prediction Shen, MemBrain: an easy-to-use online webserver for transmembrane protein structure prediction, Nano-Micro Lett. 10 (2018) 2-9... X Yin,J Yang,F Xiao,... - 《纳微快报:英文版》 被引量: 0发表: ...
Therefore, the main goal of our study was to investigate the 3D structure of bovine herpesvirus 1 - encoded UL49.5 protein. The final structure of the inhibitor was established using circular dichroism (CD), 2D nuclear magnetic resonance (NMR), and molecular dynamics (MD) in membrane mimetic ...
Membrane proteins are encoded by approximately a quarter of human genes. Inter-chain residue-residue contact information is important for structure prediction of membrane protein complexes and valuable for understanding their molecular mechanism. Althoug
All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences Transmembrane β-barrels (TMBs) carry out major functions in substrate transport and protein biogenesis but experimental determination of their 3D structur... S Hayat,C Sander,DS Marks,... - 《Proceedings of the ...
structure predictionprotein foldingA hallmark of membrane protein structure is the large number of distorted transmembrane helices. Because of the prevalence of bends, it is important to not only understand how they are generated but also to learn how to predict their occurrence. Here, we find ...
- 《Protein Science》 被引量: 210发表: 2002年 TMBpro: secondary structure, beta-contact and tertiary structure prediction of transmembrane beta-barrel proteins. Motivation: Transmembrane 尾-barrel (TMB) proteins are embedded in the outer membranes of mitochondria, Gram-negative bacteria and chloroplast...
Structure Prediction of the Transmembrane Region of Alpha- and Beta- Secretases using Replica-Exchange Molecular Dynamics Simulations, and the Interaction between Amyloid Precursor Protein and Themdoi:10.1016/J.BPJ.2020.11.414Kaori YanaginoN. Miyashita...