S., Klutsch, D., Schaffner-Barbero, C., and Hamoen, L. W. (2015). Transmembrane protein sorting driven by membrane curvature. Nat. Commun. 6, 8728. doi: 10.1038/ncomms9728Strahl, H. et al. Transmembrane protein sorting driven by membrane curvature. Nat Commun 6, 8728 (2015)....
Membrane Proteins Advances in Protein Chemistry and Structural Biology Book series2022, Advances in Protein Chemistry and Structural Biology Simen Hermansen, ... Jack C. Leo Explore book 1 Introduction Transmembrane proteins fall into two major classes. The transmembrane domains of the more abundant, ...
Computationally designed peptide inhibitors of protein-protein interactions in membranes. We successfully applied this method to design membrane-spanning peptides targeting the transmembrane domains of the αIIb subunit of integrin αIIbβ3. ... GA Caputo,RI Litvinov,W Li,... - 《Biochemistry》 被...
To infer function as a zinc transporter, we first studied the membrane topology of heterologously expressed TMEM163 protein. Contrary to its predicted orientation, we found that both the N- and C-terminus regions of TMEM163 lie at the extracellular rather than intracellular milieu. To test ...
Transmembrane proteins are widely located in the plant cell with unique structure and crucial physiological function.The research advances on the physi-chemical character,structure predictional methods and physiological function of plant transmembrane proteins were summarized.With the further study of plant ...
We show that TMEM68 is an integral membrane protein and orients both, the N- and C-terminus towards the cytosol. Live cell imaging demonstrated that TMEM68 is localized mainly at the endoplasmic reticulum (ER), but not at cellular lipid droplets (LDs). The positioning of TMEM68 at the ...
Transmembrane protein topology prediction using support vector machines Alpha-helical transmembrane (TM) proteins are involved in a wide range of important biological processes such as cell signaling, transport of membrane-impe... T Nugent,DT Jones - 《Bmc Bioinformatics》 被引量: 480发表: 2009年 ...
Programmed cell death can be divided into apoptosis and autophagic cell death. We describe the biological activities of TMEM166 (transmembrane protein 166, also known as FLJ13391), which is a novel lysosome and endoplasmic reticulum-associated membrane protein containing a putative TM domain. Overexpre...
The core of the retrovirus Murine leukemia virus (MLV) consists of the Gag precursor protein and viral RNA. It assembles at the cytoplasmic face of the cell membrane where, by an unclear mechanism, it collects viral envelope proteins embedded in the cell membrane and buds off. The C-terminal...
The protein folding in membranes is complicated because the lipid interior of the membrane is non-polar, thus making no separation of electrical charges. Therefore, a stable protein must place non-polar, water-fearing residues on its surface and pack its polar, water-loving ones inside, just ...