Protein synthesis is frequently deregulated during tumorigenesis. However, the precise contexts of selective translational control and the regulators of such mechanisms in cancer is poorly understood. Here, we uncovered CNOT3, a subunit of the CCR4-NOT complex, as an essential modulator of translation...
We measured translation diversity of a single sentence as the number of all unique translations produced by the MT system at hourly checkpoints during training. Comparing translation diversity between block-BT and mix-BT on the WMT13 newstest, we observed block-BT to have greater translation ...
However, cancer relapse and mortality rates are still too high; thus, there is an urgent need for further improvement. Indeed, lack of cancer specificity is a major shortcoming, as it underlies side effects and greatly hinders the effectiveness of current therapy (Wang and Lippard, 2005, Zug...
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