proteases to inhibit translation, the time course of eIF4G cleavage should be compared to the time course of any increase in PTC-containing mRNA abundance, as the proteases can cleave cellular proteins in addition to eIF4G, although at different (generally slower) rates than they cleave eIF4G....
Using metabolic labeling, we visualize higher translation rates in the progenitors of later-born Satb2-expressing neurons, driving the synthesis of protein translation regulators in later-born cortical lineages. We reveal fundamentally different dynamics of protein synthesis rates during differentiation of ...
I am using translation software to aid or speed up the translation process but use them for reference only, it had never replaced the brain and its judgment for the best words to use and the best way to express in another language that sound local and fluent to the native readers. Quite ...
Specifically, the unbalanced accumulation of ribosome during early translation elongation in response to RocA indicates ribosome stalling, which should lead to reduced rates of protein synthesis4,54. To confirm the inhibition of ERG protein synthesis due to disrupted translation elongation, we performed ...
Also known as the historical method, thetemporal methodconverts the currency of a foreign subsidiary into the currency of the parent company. The temporal method is used when the local currency of the subsidiary is not the same as the currency of the parent company. Differing exchange rates are...
Summary This chapter explores the foreign currency translation. Revenues and expenses that have occurred throughout the current fiscal year are converted at a weighted-average rate of exchange for the entire year. A preferable approach is to convert them at the exchange rates in effect on the ...
Since exchange rates are constantly fluctuating, it can cause difficulty while accounting for foreign currency translations. Instead of simply using the current exchange rate, businesses may look at different rates either for a specific period or specific date. ...
This makes suboptimal growth rates during the production processes necessary and consequently leads to lower specific productivities (Buchetics et al., 2011; Maurer et al., 2006). To understand regulatory changes across different growth rates, several transcriptomics studies have been performed in ...
Because rain rates span a very large range within TCs (usually including weak, moderate, and heavy rain), how do these different types of rain intensities change with translation speed? On a global scale, the probability of weaker rain rates (<1 mm h–1, mostly the weak rain) decreas...
(Supplementary Fig.15a). Typically, the RBS deletion increases the mRNA degradation rate, which results in less mRNA at the steady state47. To take into account the rapid degradation of RBS-deleted mRNA, we measured the degradation rates of LacZ mRNA with and without the RBS. The half-life...