Define Transgenic Product. means any product constituting (i) Mice or Future Generation Mice, (ii) Genetic Material from Mice or Future Generation Mice, or (iii) an Antibody-Secreting Cell.
这节录在哺育。[translate] aLv Jinke I and you not divide Lv Jinke I和您不划分[translate] aPower plug 电源插头[translate] aStudies of intestinal stem cells using normal, chimeric, and transgenic mice. 小肠干细胞的研究使用正常,虚构和transgenic老鼠。[translate]...
We have used homologous recombination in ES cells to engineer B cell-deficient mice that are incapable of expressing endogenous immunoglobulin heavy and ka... N Lonberg,D Huszar - 《International Reviews of Immunology》 被引量: 477发表: 1995年 AID Is Essential for Immunoglobulin V Gene Conversion...
The pooled whole blood and plasma have been inoculated into transgenic mice for limiting dilution titrations that will quantify their exact level of infectivity, thus increasing their value to researchers. A protocol for sharing or sale of these resources has been prepared and samples have already ...
Three to six 30-day-old TG F1 mice from each line were randomly selected for analysis. Endogenous salivary mNGF concentration also was measured by ELISA for mice of some of the lines. Each value is present as Mean ± SEM. NG means no germline transmission of transgene in TG founder ...
Briefly, during the navigation test, the mice were trained to escape onto the platform within 60 s in 5 consecutive days. If the animal could not find the platform in the permitted 60 s, it was directed to the platform and stayed on the platform for at least 15 s. On the 7th day, ...
(Mean ± SEM, n = 12 mice for each group, one-way ANOVA with Dunnett’s multiple-comparisons test, * as compared to WT mice, # as comparison to hAPP/hMAPT mice). Full size image Delta-secretase triggers AD-like pathologies and cognitive impairments in hAPP/hMAPT double-...
Second, transgenic mice have been widely used in medical research, particularly in the generation of transgenic animal models for human disease studies (Lathe and Mullins, 1993). More recently, it has been proposed to use transgenic pigs as organ donors for xenotransplantation by expressing human ...
-dependent cytotoxicity with Rituxan, our product exhibited a higher binding affinity for FcγRIIIα and a greater antibody-dependent cellular cytotoxicity. Accordingly, our recombinant mAb demonstrated a superior efficacy over Rituxan against B-cell lymphomas in severe combined immunodeficiency mice. ...
As shown in Figure 3, the intense staining of CRALBP was observed in cells lining the retinal ILM in AR-Tg mice. Cells in this region of nontransgenic controls were also positive for CRALBP immunostaining, but at a lower intensity when compared with AR-Tg (Figure 3). Immunostaining for ...