A variety of mechanisms are engaged in sex determination in vertebrates. The teleost fish swamp eel undergoes sex reversal naturally and is an ideal model for vertebrate sexual development. However, the importance of proteome-wide scanning for gonad reve
Development of two types of hepatocellular carcinoma in transgenic mice carrying the SV40 large T-antigen gene. Carcinogenesis. 1991 Nov; 12 (11):2059–2062.Araki, K., Hino, O., Miyazaki, J., Yamamura, K., 1991. Development of two types of hepatocellular carcinoma in transgenic mice ...
Follicular lymphoma (FL) is the second most common subtype of adult B-cell NHL in Western countries and is characterized by the chromosome translocation t (14;18). This abnormality promotes tumor cell survival through overexpression of the anti-apoptotic protein Bcl-2. Of interest, mice overexpres...
(A–C) Transverse sections of control extensor digitorum lognus (EDL) and soleus (SOL) muscles from wildtype animals, as well as soleus muscle of muscle-specific knock-out and overexpression of PGC1α (PGC1α-MKO, and MCK-PGC1α, respectively); transgenic mice were stained for slow MHC ...
Interleukin (IL)-4-independent Induction of Immunoglobulin (Ig)E, and Perturbation of T Cell Development in Transgenic Mice Expressing IL-13 13 transgenic lines expressed 10–100-fold higher levels of serum IgE than their littermate controls, but had normal levels of other serum Ig isotypes......
Hyperplasia in Transgenic Mice Lymphocytic Infiltration and Gastric Mucous Neck Cell The Mutant Kras Oncogene Causes Pancreatic Periductal We have generated a novel mouse model in which the cytokeratin 19 promoter, specifically active in pancreatic ductal cells but not other cell types of ... F. S...
1. Overexpression of NPM|[ndash]|ALK induces different types of malignant lymphomas in IL-9 transgenic mice [J] . Karin Lange, Wolfgang Uckert, Thomas Blankenstein, Oncogene . 2003,第4期 机译:NPM | n | ALK的过表达在IL-9转基因小鼠中诱导不同类型的恶性淋巴瘤 2. The oncogenic fusion...
11 The characteristic ground glass appearance of hepatocytes could be in vitro induced by the overproduction of large surface antigen in ER.12, 13 Transgenic mice that strongly overproduce large surface antigen can also form GGHs in the liver.14 Although GGHs are consistently associated with large ...
Most previous studies used mouse models of AD, as the tissue of transgenic mice is more easily available than human tissue and usually Röhr et al. acta neuropathol commun (2020) 8:222 Page 8 of 13 Fig. 5 Statistical analysis. The boxplots present spectroscopic ratios derived ...
Adult male and female transgenic mice were used in this study (2-5 months of age). We used the following Cre transgenic lines to isolate and manipulate specific cell types in the superior colliculus: Grp-KH288-Cre and Ntsr1-GN209-Cre [18], and Pvalb-IRES-Cre [46]. In a subset of ...