L Montoliu,S Chávez,M Vidal - 《Transgenic Research》 被引量: 85发表: 2000年 Transgenic Animals in Toxicology1 Recent advances have been made in the characterization of anumber of transgenic animal models. These animal models haveprovided a powerful toxicological tool for studying in vivochemical...
This paper briefly reviews the basic concepts, principle, characteristics and applications of the mammary gland bioreactor of transgenic animals,especially summarizing its current research status and bright future,meanwhile discusses the problems existed. 展开 关键词: transgenic animals mammary gland ...
In particular, a method based on the use of a transgenic animal, wherein the transgenic animals tolerised (tolerised) and measuring the immune response against a specific antigen and then exposed to the antigen variants. 在一个实施方案中,所述转基因动物是人类II类MHC分子的转基因小鼠并且变异抗体...
transgenic animals with the deepen research of SSCs.Then,the biological characteristics of SSCs as well as the principle of carrying exogenous gene into animal genome was described to clarify its theoretical mechanisms in preparation of transgenic animals,meanwhile,the research status of spermatogonial ...
In conclusion, we demonstrated that transgenic cattle using the DNA transposon system could be efficiently generated, and all those animals could be a valuable resource for agriculture and veterinary science. Transgenesis is an important tool to understand gene function in mammals. Based on isolation ...
Transgenic rabbits expressing the bovine growth hormone (bGH) gene in liver and kidney were obtained to study the long-term effects of chronic exposure to GH in nonrodent animals. These rabbits presented high levels of bGH and insulin-like growth factor I in serum. In spite of chronic exposure...
TRANSGENIC ANIMALS EXPRESSING VON WILLEBRAND FACTO 优质文献 相似文献 参考文献Interaction of the von Willebrand factor (vWF) with collagen. Localization of the primary collagen-binding site by analysis of recombinant vWF a domain pol... The von Willebrand factor (vWF) mediates platelet adhesion to the...
transgenic animalsThe recombinant plasmids pLNCXHLF fused with human lactoferritin gene were directly injected into male rabbit's testis and male goat's spermaductus.The transfected males were fertilized with females one month later. Using F 1/R 1 PCR system and southern blotting,the transgenic ...
Typical medical application includes ;as a source of biologically active proteins, as donors in xenotransplantation , as disease models for the development of new treatments, antibody production in transgenic animals, blood replacement and for a research in cell and gene therapy. Despite having these ...
Nowadays,with more and more transgene animals appeared,transgene which is an important biotechnology become one of the most hottest research field. This article reviewed that current situation of molecular breeding of swine in China,transgene technologies and its application ,indicated existed problems.关...