protein–protein interactionRESTthyroid hormone receptortranscriptional repressionThe zinc finger protein REST (RE‐1 silencing transcription factor) is a transcriptional repressor that inhibits neuronal gene transcription in non‐neuronal tissues. REST may represent a master regulator of neuronal gene ...
Interaction of Transcriptional Repressor ArgR with Transcriptional Regulator FarR at the argB Promoter Region in Corynebacterium glutamicum.doi:10.1128/AEM.01610-10In Corynebacterium glutamicum, the ArgR protein, a transcriptional repressor, affects the expression level of the argB gene through binding to ...
The physical interaction of HvWRKY38 and BPBF repressors is demonstrated via bimolecular fluorescence complementation assays. These data suggest that the expression of Amy32b is modulated by protein complexes that contain either activators (e.g. HvGAMYB and SAD) or repressors (e.g. HvWRKY38 and...
We have defined the LUG/LUH, Flo8, single-strand DNA-binding protein domain of LUG as both necessary and sufficient for the interaction with SEU and two domains of LUG as important for its repressor function. Our work provides functional insights into plant transcriptional corepressors and ...
et al. An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3. Cell 80, 777–786 (1995). CAS PubMed Google Scholar Gordan, J. D. et al. HIF-α effects on c-Myc distinguish two subtypes of ...
ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation du... 1995. ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by ...
Our work and other studies support a model in which E2F4 should not simply be viewed as a repressor of transcription and cell cycle progression. Future work will be needed to identify the different protein complexes that E2F4 contributes to and the plethora of cellular functions that are control...
to function. These transcription activators are sequence specific DNAbinding proteinsthat increase the frequency oftranscription initiation.Transcriptional activatorsand repressors share many properties and often exert their effect in response to specific environmental signals. A small number of transcription ...
7. About 20 classes of one-component regulatory systems were identified in bacteria, many of which are characterized functionally and structurally up to atomic resolution7,8,9. One-component regulators of the TetR (Tetracycline repressor protein class D) family are homodimers and contain a C-...
To pinpoint the mechanism of UBR5 action on RLRs, we searched for UBR5-interacting proteins. Of note, in two independent screenings for protein-protein interactions, UBR5 was shown to interact with TRIM2823,24, which is an epigenetic repressor ofRLRs25. Indeed, after revisiting the initial ...